An observational study in Catheterization, Central Venous, Echocardiography, Transesophageal and Anatomic Landmarks, sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-01.
Sponsored by Ain Shams University · Observational
The primary aim of this study is to derive a prediction rule to estimate the required length for placement of the CVC tip at the mid-point of the SVC from simple anatomical landmarks that are consistent with the known surface projections of the great veins. The accuracy of this rule will be examined using TEE and is intended for adult patients undergoing cannulation of the right IJV utilizing a middle approach. As a secondary aim, we will examine the performance of this suggested rule as contrasted with two other popular methods for estimation of the CVC length, the Peres formula and the C-length method.
Before induction of anesthesia
Three sets of measurements will be obtained for each participant before induction of anesthesia:
The right internal jugular vein (IJV) will be cannulated under ultrasound guidance using the Seldinger technique.
After puncture of the IJV a J-wire will be advanced through the trocar until the J-end of the guidewire is visualized at the RA-IJV junction via the TEE.
The CVC catheter will be passed over the guidewire to the RA-SCV junction. The guidewire will be removed and the catheter will then be retracted under TEE guidance until the tip in visualized at 3.0 cm above the RA-SVC junction as measured with the TEE cursor. If the distal (upper) portion of the SVC could not be visualized, the catheter would be retracted for 3 cm as guided by the 1-cm gradations on the CVC.
Post-operative After operation, plain PA CXR will be obtained at the intensive care unit (ICU) to verify the position of the CVC tip in relation to the carina.
Statistical Analysis:
The length of the catheter required to place the tip at the mid SVC will be regressed on the C-length or the surface distance to obtain a predictive equation. The accuracy of either equation will be assessed by estimation of the standard error of the estimate (SEest).
Ain Shams University is the lead sponsor of 1,876 studies on the registry; 423 are open to participants now.
Of its 32 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Adult subjects of either sex who are scheduled for elective cardiac surgery in whom echocardiography is indicated or recommended will be eligible.
Exclusion Criteria:
The right internal jugular vein will be cannulated under transesophageal echocardiographic (TEE) guidance in order to place the catheter tip in the mid-SVC. The length of the catheter required to place the tip at the mid-SVC as guided by TEE will be regressed on the C-length or on the distance from the entry point to the surface point corresponding to the mid-SVC on the chest wall in order to obtain a predictive equation. The accuracy of either equation will be assessed by estimation of the standard error of the estimate (SEest).
Also known as: Transesophageal echocardiography (to guide placement of central venous catheter tip at mid-SVC)
Accuracy of surface landmarks for prediction of CVC depth required to place the CVC tip at the mid-SVC.
Difference between actual length required to place the CVC tip at the mid-SVC as guided by TEE and the distance from the entry point to the surface point corresponding to the mid-SVC on the chest wall.
Time frame: Outcome will be assessed at completion of catheterization procedure
Accuracy of C-length for prediction of CVC depth required to place the CVC tip at the mid-SVC.
Difference between actual length required to place the CVC tip at the mid-SVC as guided by TEE and the C-length.
Time frame: Outcome will be assessed at completion of catheterization procedure
Plan to share: No
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This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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Ain Shams University