An interventional study of 405nm light in Pathogen Transmission, sponsored by Northwestern Medicine. Status unknown at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-02-12.
Sponsored by Northwestern Medicine · Not applicable, Interventional, and Prevention
Operating room S. aureus exposure has been directly linked to postoperative infections and is therefore an important target for infection prevention. Visible light (non-ultraviolet spectrum) at 405nm has been shown to be germicidal. We hypothesize that use of this light in operating rooms will reduce S. aureus transmission occurring within and between patients and reduce surgical site infections (SSIs). Visible light is safe for routine, continual exposure, and is less harmful than sunlight. We plan to install ambient, germicidal lighting in 4 operating rooms. This ambient light is not directly applied to patients (does not involve the surgical procedure lights). Patients will undergo surgery according to usual practice. We will conduct a case-control study where operating rooms with surgeries with the lights are matched to operating rooms with surgeries without lights.
In Aim 1, 4 OR-pairs will be observed each day over an anticipated 103 working days for the primary outcome of S. aureus transmission events over a total minimum study period of 5.2 months (103 working days).
Northwestern Medicine is the lead sponsor of 5 studies on the registry; none are open to participants now.
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Exclusion Criteria:
In this room, surgeries will be performed under ambient light including the wavelength 405nm
Device: 405nm light
In this room, surgeries will be performed under ambient light from regular phosphorescent light does not include 405nm frequencies
In this room, surgeries will be performed under ambient light including the wavelength 405nm
Staphylococcus aureus transmission rate
We will be assessing the transmission of bacteria to the patient during the case and from previous cases to subsequent cases.
Time frame: sequential surgeries on the same 1 day
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Feb 2020. You cannot join it, but the record below documents what was studied.
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