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CompletedNCT04248660Updated Jan 30, 2020

Uterine Artery Doppler and 11-14 / 20-22 Weeks of Gestation Pregnancy

An observational study in Pregnancy Related, sponsored by Kanuni Sultan Suleyman Training and Research Hospital. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2020-01-30.

Sponsored by Kanuni Sultan Suleyman Training and Research Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
750
Ages
18 Years to 45 Years
Sex
Female
01

Study summary

Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery type on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes).

Read the detailed description

The first and second trimester perinatal examination results performed by the same operator from pregnant women who have applied to the clinic since the first trimester are removed from the ViewPoint 6.0 server and database and their uterine artery doppler values (uterine artery PI and RI values, presence of uterine artery notch), placental location, gestational week of measurement, blood pressures, PAPP-A and hCG MoM values, obstetric results (type of birth, week, weight, ante-postpartum complications), data to be generated from other hospital records will be saved to the base

02

Conditions studied

  • Pregnancy Related

Keywords

  • Uterine artery doppler
  • type of delivery
  • obstetric outcomes
03

In context

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital is the lead sponsor of 216 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients who had uterine artery doppler measurements and delivered at 11-14 weeks and 20-22 weeks of pregnancy will be the study group. these patients; Doppler results will be classified according to pregnancy results, and the classification of these measurements according to type of delivery; and the effect of delivery on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes) will be examined.

Inclusion criteria

  • Gestational age 11-14. applying to the outpatient clinic at week
  • Single spontaneous pregnancy
  • Having a first pregnancy (primigravid nullipar) or having given birth once (primipar) (first birth by vaginal route or cesarean)
  • Result of previous pregnancy with live birth (term delivery without obstetric complication)
  • No intrauterine growth restriction in the first pregnancy
  • Women who gave birth by cesarean section were not placed due to caesarean indication due to placental location-invasion anomaly, maternal chronic disease (hypertension, diabetes, coronary artery disease, etc.), placental detachment.

Exclusion criteria

Exclusion Criteria:

  • Multiple pregnancies
  • Pregnancies with assisted reproductive techniques
  • Placental anomaly in previous pregnancy
  • Maternal chronic hypertension, preeclampsia, history of diabetes
  • Pregnant women who smoke
  • The presence of fetal chromosomal or structural anomaly
  • two or more cesarean sections
  • Having undergone non-cesarean surgery (myomectomy, septum or polyp resection ... etc)
  • Presence of uterine structural anomaly
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
750 participants (actual)
Patient registry
No

Groups and cohorts

  • Uterine artery doppler measurements

    Uterine artery doppler measurements will be made in the same patients at 11-14 weeks and 20-22 weeks of pregnancy. Doppler results will be classified according to pregnancy results and primary results will be doppler findings.

    Other: uterine artery doppler measurement

Interventions

  • Otheruterine artery doppler measurement

    The effect of delivery type on changes in uterine blood flow will be investigated. Doppler results groups will be defined according to the effect of deviations in uterine blood flow on neonatal and perinatal results.

06

What researchers measure

Primary outcomes

  1. Doppler results of 11-14 weeks of gestation in patients with previous cesarean section

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

    Time frame: 10 months

  2. Doppler results of 11-14 weeks of gestation in those who gave birth beforehand

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

    Time frame: 10 months

  3. Doppler results of 20-22 weeks of gestation in patients with previous cesarean section

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

    Time frame: 10 months

  4. Doppler results of 20-22 weeks of gestation in those who gave birth beforehand

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

    Time frame: 10 months

07

Study locations

1 site
  • Kanuni Sultan Süleyman Training and Research Hospital
    Istanbul, 33404, Turkey
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04248660
Lead sponsor
Kanuni Sultan Suleyman Training and Research Hospital
Responsible party
Pınar Kadirogulları (principal investigator, Pınar kadirogullari, M.D, Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital) — Principal investigator
First posted
Jan 30, 2020
Start date
Jan 1, 2016
Primary completion
Jan 1, 2020
Completion
Jan 1, 2020
Last update
Jan 30, 2020

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.

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