ClinicalTrials.gg
CompletedNCT04211818GLUCOPULSEUpdated Sep 30, 2025

Analysis of the Glycemic Profile of People Suffering From Compulsive Eating Disorders Aiming to Offer an Innovative Nutritional Approach (GLUCOPULSE)

An interventional study of Eating Behavior and Blood glucose records in Bulimia, Binge Eating and Blood Glucose, Low, sponsored by University Hospital, Montpellier. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-09-30.

Sponsored by University Hospital, Montpellier · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

Eating Disorders (ED) are a major public health problem. Current care remains only partially effective and the pathophysiology of the disorders remains to be deepened. With regard to compulsive ED (bulimia and binge eating disorder), our clinical experience suggests that one of the major triggers for crisis may be related to glycemia. In fact, bulimia could be considered as a vicious circle where the binge eating disorder is going to be followed by a food restriction in order to control weight , putting the subject in a situation of "energy deficiency" which will favor the emergence of new crises . Technological advances have resulted in the emergence of new measuring devices, such as "tracking", which records continuous glycemia, which would allow us to explore these clinical hypotheses.

Read the detailed description

This is an open-label, exploratory, proof-of-concept study.

20 patients will be recruited from the day hospital of the Endocrinology and Nutrition Department of the University Hospital of Montpellier, Lapeyronie and from Emergencies and Post-psychiatric Emergencies Department.

During the inclusion visit, the dietician will explain to the patient the use of the dietary book and the glycemic sensor which will be allocated to it. The patient will also answer to self-questionnaires about his eating behavior.

No nutritional approach will be addressed so as not to alter the patient's eating behavior and not to influence the results.

They will be followed-up during 14 days.

02

Conditions studied

  • Bulimia
  • Binge Eating
  • Blood Glucose, Low
  • Crisis State
  • Compulsion
03

In context

Bulimia

173 studies on the registry are indexed under Bulimia; 33 are open to participants now.

This study's enrollment of 20 is below the median of 60 across 143 interventional studies indexed under Bulimia.

Browse Bulimia studies →

Lead sponsor

University Hospital, Montpellier is the lead sponsor of 1,261 studies on the registry; 224 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Subject suffering from eating disorders with at least 3 episodes of bulimia per week for at least 2 months
  • Subject affiliated to a health insurance or beneficiary of such a plan
  • Subject able to understand the nature, purpose and methodology of the study
  • Subject signed

Exclusion criteria

Exclusion Criteria:

  • Subject suffering from eating disorders such as anorexia nervosa
  • Subject unable according to the investigator's opinion to keep updated a dietary book or to perform correctly the glycemic recordings
  • Subject suffering from somatic pathology (ex: diabetes) or psychiatric pathology assessed by the MINI (ex : severe current major depressive episode) that may interfere with the protocol according to the the investigator
  • Major subject legally protected (guardians or curators) or deprived of freedom by judicial or administrative order
  • Pregnant or nursing woman
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Patients

    Behavioral: Eating Behavior · Biological: Blood glucose records

Interventions

  • BehavioralEating Behavior

    A dietary book will be given to the patient and will be filled by this one during 14 days

  • BiologicalBlood glucose records

    A glycemic sensor will be placed at the back of the patient's arm

06

What researchers measure

Primary outcomes

  1. Frequency of episodes of bulimia (measured from the dietary book) according to the interstitial glucose levels

    Each information entered on the dietary book will be positioned on a chronological axis allowing to identify precisely when the eating disorder occurred

    Time frame: At the return of the dietary book (14 days after enrollment)

Secondary outcomes

  1. Levels of impulse to make a crisis and food obsession and hunger depending on interstitial glucose levels

    Each information entered on the dietary book will be positioned on a chronological axis allowing to identify precisely when the eating disorder occurred

    Time frame: At the return of the dietary book (14 days after enrollment)

  2. Dietary patterns

    Measured by the Emotional Appetite Questionnaire (EMAQ), 1 represent a food intake much smaller than usual ; 9 represent a food intake more significant than usual ; 5 represent a food intake as usual

    Time frame: At enrollment

07

Study locations

1 site
  • University Hospital
    Montpellier, 34 295, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04211818
Responsible party
Sponsor
First posted
Dec 26, 2019
Start date
Oct 16, 2020
Primary completion
Aug 25, 2022
Completion
Jul 1, 2023
Last update
Sep 30, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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