CClinicalTrials.gg
Status unknownNCT04174027Updated Nov 22, 2019

The Effect of Perturbration on Balance Control in Adults

An observational study in Chronic Ankle Instability, sponsored by Meir Medical Center. Status unknown. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-11-22.

Sponsored by Meir Medical Center · Observational

The sponsor has not verified this record recently (last verified Nov 2019), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
100
Ages
18 Years to 50 Years
Sex
All
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Study summary

Balance control in respond to an unexpected platform perturbration during standing and walking: comparison between individuals with chronic ankle instability and healthy individuals.

Read the detailed description

An unexpected postural perturbration is a major risk factor of falls and injuries during gait. A postural perturbration is a sudden change in conditions that displaces the body posture away from equilibrium. Reactive postural control response is an immediate ( 70-120 ms ) automatic "like reflex" response which is initiated by unexpected postural perturbration in order to maintain balance. Even among young healthy adults there could be a problem in balance performance which does not become evident untill a slip or a trip or any other sudden perturbration happens. Thus a simple test of pertubration while standing or walking can identify a problem .

This study is comparing the reactive postural control of physical education students who suffer from chronic ankle instability (CAI) to healthy students on a Perturbation Treadmill. The device consists of a treadmill mounted on a moving force plate platform. The platform moves in the medial/ lateral plains to simulate a slip and a trip in both the standing and walking phase. Their reactive postural control is tested in a few conditions: standing on both legs - eyes open and eyes closed, in tandem standing, standing on one leg and in walking. In each condition the perturbration is given every 5-15 seconds in different speed and in unexpected direction (right /left). Lost of balance control is any change in the original location of the foot in standing conditions or stepping out of the treadmill.

02

Conditions studied

  • Chronic Ankle Instability

Keywords

  • Chronic ankle instability ( CAI )
  • Perturbration
  • reactive postural control
  • balance
  • center of pressure - COP
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In context

Lead sponsor

Meir Medical Center is the lead sponsor of 389 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Physical education students from Zinman College in Wingate

Inclusion criteria

  • age 18-50
  • good health
  • active people

Exclusion criteria

Exclusion Criteria:

  • Body weight greater than 135 kg
  • Bone instability (non-consolidated fractures, unstable spinal column, severe osteoporosis)
  • Head damage in the year prior to the study
  • Diabetics or Unstable circulation
  • Cardiac (blood) contraindications
  • Vestibular problem
  • Neurological deficits
  • Mechanical ventilation problem
  • Severe vascular disorders of the lower limbs
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Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. static balance control in reaction to perturbration

    The angle velocity at the ankle at the moment of loosing postural control while standing

    Time frame: 20 minutes

  2. dynamic balance control un reaction to perturbration

    the speed of perturbration at the moment of loosing balance while walking

    Time frame: 10 minutes

Secondary outcomes

  1. Time to returning to original condition

    How much time it takes to come back to the original step (Center of Pressure - COP) after the perturbration

    Time frame: 30 minutes

Other outcomes

  1. movement inside the foot during balance control.

    The changes in center of pressure (COP) amplitude height

    Time frame: 30 minutes

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 22, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04174027
Lead sponsor
Meir Medical Center
Responsible party
Sponsor
First posted
Nov 22, 2019
Start date
Dec 15, 2019 (estimated)
Primary completion
Oct 15, 2020 (estimated)
Completion
Dec 15, 2020 (estimated)
Last update
Nov 22, 2019

Study contacts

Alon Eliakim, MD
Contact
Eliakim.Alon@clalit.org.il
972-9-7471596
Michal Pantanowitz, PhD
Contact
michal.pantanowitz@clalit.org.il
972-9-7471596

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2019. You cannot join it, but the record below documents what was studied.

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