An observational study in Tinnitus, Subjective, Hearing Loss and Otorhinolaryngologic Diseases, sponsored by University Hospital Sestre Milosrdnice. Status unknown at 1 site in Croatia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-11-20.
Sponsored by University Hospital Sestre Milosrdnice · Observational
The aim of this study is to evaluate hearing characteristics in patients with and without tinnitus using DPOAE and specific tinnitus severity index (TSI) and tinnitus handicap inventory (THI) questionnaires in both groups.
Purpose of the research:
Demonstrate that the characteristics of tinnitus depend on the presence and magnitude of hearing loss.
Research participants:
150 patients coming for further audiological treatment due to tinnitus. Data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be performed.
Tinnitus affects 17% of the total population and as many as 33% of the elderly and is the primary symptom in 60% of patients referred for audiological treatment. Tinnitus is the perception of sound without external stimuli. Its pathophysiological basis is unknown and therefore its treatment is difficult and understanding of other disorders that occur in the auditory system is impeded. The auditory system has a complex structure that consists of the organs of Corti, the afferent and efferent conduction pathways, the cortical auditory center and the connections that allow their integration. The pathology that develops in any of these parts leads to a heightened perception of sound by unknown mechanisms. Patients can describe tinnitus in a variety of ways, such as sea noise, rapid flow, ringing, howling and whistling. The measurement of otoacoustic emissions by distortion products (DPOAE) is the main method that allows the evaluation of the mechanical activity of the cochlea in patients with tinnitus. In these patients, hyperacusis plays an important role and it can often be a precursor to tinnitus. The aim of this study is to evaluate hearing characteristics in patients with and without tinnitus using DPOAE and specific tinnitus severity index (TSI) and tinnitus handicap inventory (THI) questionnaires in both groups.
Research goal:
Identify differences in tinnitus characteristics in patients with and without significant hearing impairment.
Purpose of the research:
Demonstrate that the characteristics of tinnitus depend on the presence and magnitude of the visual hearing impairment.
Research participants:
150 patients coming for further audiological treatment due to tinnitus. The data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be made.
Research plan:
A prospective cohort nonrandomized study of non-masked parallel paired groups. When receiving patients at the Hearing and Balance Center, the inclusion criteria for admission to the study are adulthood (> 18 years), tinnitus as the primary reason for referring to diagnostic treatment, and consent to complete two on-site tinnitus questionnaires. Exclusion criteria are conductive hearing impairment and incomplete questionnaires. It is planned to evaluate the differences in tinnitus character between groups of patients with and without significant hearing impairment with respect to the objective parameters of the audiogram and DPAOE.
Primary Outcome:
Identification of key differences in subjective and objective characteristics of tinnitus in patients with and without noticeable hearing impairment.
There is no risk involved in this research.
1,092 studies on the registry are indexed under Hearing Loss; 235 are open to participants now.
This study's planned enrollment of 150 is above the median of 87 across 270 observational studies indexed under Hearing Loss.
Browse Hearing Loss studies →University Hospital Sestre Milosrdnice is the lead sponsor of 27 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with and without hearing loss suffering from tinnitus, scheduled for diagnostic in a tertiary audiological center.
Exclusion Criteria:
Patients with tinnitus and average speech-frequency tonal audiogram threshold \>30 dB
Behavioral: Tinnitus Handicap Inventory Test
Patients with tinnitus and average speech-frequency tonal audiogram threshold \<30 dB
Behavioral: Tinnitus Handicap Inventory Test
A prospective cohort nonrandomized study of non-masked parallel paired groups. The data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be performed.
Also known as: Distortion Product Otoacoustic Emission
Establishing correlations between DPOAE, TA, and THI values
Evaluating whethere there are certain characteristics of tinnitus correlated with patients with and without hearing loss
Time frame: 2 hours
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Nov 2019. You cannot join it, but the record below documents what was studied.
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University Hospital Sestre Milosrdnice