An observational study in Critically Ill, Major Trauma and Anesthesia, sponsored by Helsinki University Central Hospital. Status unknown at 6 sites in Finland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-10-28.
Sponsored by Helsinki University Central Hospital · Observational
Brain oxygenation of adult patients undergoing prehospital emergency anesthesia is monitored using noninvasive near-infrared spectroscopy. Patients are afterwards interviewed to define neurological outcome to measure quality of life. The purpose of this study is to reveal the risk factors of prehospital anesthesia related cerebral desaturation events (CDE) and to define the association between CDE and survival, neurological outcome or quality of life.
1,692 studies on the registry are indexed under Emergencies; 333 are open to participants now.
This study's planned enrollment of 1,300 is above the median of 353 across 714 observational studies indexed under Emergencies.
Browse Emergencies studies →Helsinki University Central Hospital is the lead sponsor of 299 studies on the registry; 60 are open to participants now.
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Adult patients undergoing prehospital anesthesia and endotracheal intubation regardless of indication
Exclusion Criteria:
absolute drop of forehead cerebral oxygen saturation ≥ 10% from baseline for ≥ 5 minutes during prehospital anesthesia
Diagnostic Test: Cerebral near-infrared spectroscopy
no absolute drop of forehead cerebral oxygen saturation ≥ 10% from baseline for ≥ 5 minutes during prehospital anesthesia
Diagnostic Test: Cerebral near-infrared spectroscopy
Nonin H500 one-channel near-infrared spectroscopy monitor on forehead of the patient from before induction of anesthesia to arrival to hospital
Favorable neurological outcome
modified Rankin scale ≤2 (scale 0-6, 0 asymptomatic, 6 expired)
Time frame: 30 days
Cerebral desaturation event
an absolute drop of forehead cerebral saturation ≥ 10% from baseline for ≥ 5 minutes
Time frame: through prehospital care, approximately 60 minutes
Survival
Survival
Time frame: 30 days
Survival
Survival
Time frame: 365 days
Favorable neurological outcome
modified Rankin scale ≤2 (scale 0-6, 0 asymptomatic, 6 expired)
Time frame: 1 year
15D score
Heal-Related Quality of Life measured using 15-D instrument, scale 0-1 (0 = being dead, 0.0162 = being unconscious or comatose, 1 = no problems on any dimension = 'full' HRQOL)
Time frame: 1 year
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Oct 2022. You cannot join it, but the record below documents what was studied.
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Helsinki University Central Hospital