CClinicalTrials.gg
Status unknownNCT04103463Updated Sep 25, 2019

Interactive Stepping Exercise on Memory

An interventional study of Interactive stepping exercise and Home exercise in Amnestic Mild Cognitive Impairment, Interactive Stepping Exercise and Memory, sponsored by National Yang Ming Chiao Tung University. Status unknown. Open to participants aged 50 Years to 100 Years. Per ClinicalTrials.gov, last updated 2019-09-25.

Sponsored by National Yang Ming Chiao Tung University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Sep 2019), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
50 Years to 100 Years
Sex
All
01

Study summary

This is a randomized controlled trail. A total of 28 individuals with aMCI will be randomly assigned to either the ISE group or control group. The ISE intervention conducts three times a week for 16 weeks. Outcomes are measured at baseline and after intervention. The primary outcomes are the Chinese version verbal learning test (CVVLT), selective reminding test (SRT), and logic memory test (Wechsler Memory Scale). The secondary outcomes are Montreal Cognitive Assessment (MoCA) for cognitive function, and trail making test Part A \& B (TMT-A \& B), Stroop test, and 25-item Executive Interview (C-EXIT 25) for executive function.

02

Conditions studied

  • Amnestic Mild Cognitive Impairment
  • Interactive Stepping Exercise
  • Memory
  • Cognitive Function
  • Executive Function

Keywords

  • square stepping exercise
  • Amnestic mild cognitive impairment
  • Interactive stepping exercise
  • memory
  • cognitive function
  • executive function
03

In context

Cognitive Dysfunction

3,843 studies on the registry are indexed under Cognitive Dysfunction; 1,100 are open to participants now.

This study's planned enrollment of 30 is below the median of 65 across 2,808 interventional studies indexed under Cognitive Dysfunction.

Browse Cognitive Dysfunction studies →

Lead sponsor

National Yang Ming Chiao Tung University is the lead sponsor of 201 studies on the registry; 58 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age≥50 years
  • Complained of memory impairment
  • Chinese Version Verbal Learning Test 10-minute delays ≤ 6 words
  • MMSE score≥24 and CDR score=0.5
  • Activities of daily living are intact
  • DSM-IV criteria for the diagnosis of dementia is not met

Exclusion criteria

Exclusion Criteria:

  • Any significant neurologic disease other than suspected incipient Alzheimer's disease
  • Psychotic features, contraindication of exercise... which could lead to difficulty complying with the protocol
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Interactive stepping exercise group

    Other: Interactive stepping exercise

  • Active comparator
    Home exercise group

    Other: Home exercise

Interventions

  • OtherInteractive stepping exercise

    An exercise intervention based on the principle of square stepping exercise

  • OtherHome exercise

    Home exercise

06

What researchers measure

Primary outcomes

  1. Chinese version verbal learning test

    Time frame: Change from baseline at 12 week

  2. Selective reminding test

    Time frame: Change from baseline at 12 week

  3. Wechsler Memory Scale-III

    Time frame: Change from baseline at 12 week

  4. Logic memory test

    Time frame: Change from baseline at 12 week

Secondary outcomes

  1. Montreal Cognitive Assessment

    Time frame: Change from baseline at 12 week

  2. Trail making test

    Time frame: Change from baseline at 12 week

  3. Stroop test

    Time frame: Change from baseline at 12 week

  4. Executive Interview

    Time frame: Change from baseline at 12 week

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 25, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04103463
Lead sponsor
National Yang Ming Chiao Tung University
Responsible party
Yea-Ru Yang (Professor, National Yang Ming Chiao Tung University) — Principal investigator
First posted
Sep 25, 2019
Start date
Oct 1, 2019 (estimated)
Primary completion
Dec 31, 2020 (estimated)
Completion
Jul 31, 2021 (estimated)
Last update
Sep 25, 2019

Study contacts

Yea-Ru Yang
Contact
yryang@ym.edu.tw
+886228267279

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.

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