An observational study in Sepsis, sponsored by Boston Children's Hospital. Recruiting at 1 site in United States. Open to participants aged 2 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-03-17.
Sponsored by Boston Children's Hospital · Observational
In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in the lungs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood and secretions from the breathing tube of patients with sepsis so that they can work to develop therapies to prevent these cells from being harmful.
1,899 studies on the registry are indexed under Sepsis; 462 are open to participants now.
This study's planned enrollment of 75 is below the median of 160 across 931 observational studies indexed under Sepsis.
Browse Sepsis studies →Boston Children's Hospital is the lead sponsor of 598 studies on the registry; 151 are open to participants now.
Of its 31 completed or terminated interventional studies of FDA-regulated products, 18 (58%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients from 2-50 years old at Boston Children's Hospital either in an ICU with sepsis or a healthy control coming for a surgical procedure.
Case Inclusion Criteria:
Control Inclusion Criteria:
Exclusion Criteria:
Other: Sepsis
Sepsis patients in the ICU with a breathing tube
Neutrophil characteristics
measure and report β2 integrin expression on neutrophils from blood and tracheal aspirate between sepsis patients and non-sepsis patients in pediatric population
Time frame: One day
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