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CompletedNCT04054271Updated Aug 13, 2019

Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants

An observational study in Implant Tissue Failure, sponsored by Yuzuncu Yil University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 19 Years to 78 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-13.

Sponsored by Yuzuncu Yil University · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
963
Ages
19 Years to 78 Years
Sex
All
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Study summary

This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.

Read the detailed description

For a successful dental implant, optimal soft and hard tissue characteristics are required. These characteristics include appropriate bone quality and a healthy adherent keratinized gingiva that surrounds the implant neck. The most common complications are peri-implant diseases and marginal bone loss for dental implants. Marginal bone loss around the implant may be observed as a long-term complication due to microbial dental plaque-induced peri-implant inflammatory disease or may be observed in the absence of such a disease.

The immune system and genetic factors are known to have important effects on implant success, and ABO blood types are also included in the genetic factors. In the studies evaluating the association of ABO blood types with increased susceptibility to infection and various systemic diseases, it was reported that the percentages of blood types differed significantly, especially in skeletal-muscle system injuries, fractures and cardiovascular disease susceptibility. Also some researchers reported that blood types may be effective on the bacteria colonization which is the main reason of the periodontal diseases. ABO blood types may have an impact on dental implant success and survival.

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Conditions studied

  • Implant Tissue Failure

Keywords

  • Blood types, Dental implant, Marginal Bone Resorption, Implant Survival
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In context

Lead sponsor

Yuzuncu Yil University is the lead sponsor of 78 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years to 78 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

This cross-sectional study was performed on patients who had undergone implant treatment and had prosthetic rehabilitation at the Faculty of Dentistry of the Van Yuzuncu Yil University between 2010 and 2017 and who had been followed up for at least one year.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • The inclusion criteria for the study group included being 18 years of age and non-smoker, not having any systemic disease, not having undergone any hard and soft tissue augmentation during implant surgery, having implants placed at bone level, having received cylindrical form implants with SLA surface structure, not missing any follow-up visits after implant surgery evidenced with radiographic recordings, having received flat abutment, having cemented implants, and being rehabilitated with fixed prosthetic restoration.

Exclusion criteria

Exclusion Criteria:

  • No
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Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
963 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Marginal bone resorption measurements (mm) in dental implants.

    We evaluated marginal bone resorption in patients receiving implant treatment with respect to ABO blood types. These measurements will be measured by periapical radiographs. Periapical radiographs were taken with a parallel technique to measure the amount of mesial and distal bone resorption in the neck region of the implants.

    Time frame: 1 year

  2. Implant survival rates according to demographic data

    We evaluated implant survival rates by age and sex on a yearly basis

    Time frame: 1 year

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Study locations

1 site
  • Serap Keskin Tunc
    Van, 65100, Turkey (Türkiye)
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 13, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04054271
Lead sponsor
Yuzuncu Yil University
Responsible party
Serap Keskin Tunc (PhD, DDA, Assistant professor, Yuzuncu Yil University) — Principal investigator
First posted
Aug 13, 2019
Start date
Dec 15, 2017
Primary completion
Dec 15, 2018
Completion
Dec 15, 2018
Last update
Aug 13, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.

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