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CompletedNCT04040998Updated Aug 1, 2019

Compensatory Cognitive Training For Schizophrenia

An interventional study of Compensatory Cognitive Training in Schizophrenia, sponsored by Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan. Completed at 1 site in Taiwan. Open to female participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2019-08-01.

Sponsored by Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 6 months after the study started (first participant enrolled Jan 2018, registered Jul 2019).
Phase
Not applicable
Study type
Interventional
Enrollment
46
Allocation
Randomized
Ages
20 Years to 65 Years
Sex
Female
01

Study summary

This study aimed to investigate the effects of compensatory cognitive training plus treatment as usual (CCT+TAU) versus treatment as usual (TAU) on on self-esteem, self-efficacy, quality of life, and self-stigma for schizophrenia.

02

Conditions studied

  • Schizophrenia

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Keywords

  • schizophrenia
  • compensatory cognitive training
  • generalized estimating equation
  • psychosocial correlates
  • self-stigma
03

In context

Schizophrenia

3,539 studies on the registry are indexed under Schizophrenia; 473 are open to participants now.

This study's enrollment of 46 is below the median of 70 across 2,924 interventional studies indexed under Schizophrenia.

Browse Schizophrenia studies →

Lead sponsor

Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan is the lead sponsor of 5 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diagnosis of schizophrenia, based on the ICD-10 diagnostic criteria for research (World Health Organization, 1992)
  • age from 20 to 65
  • attending day care center regularly for at least 3 months
  • taking stable dose of medication for at least 3 months

Exclusion criteria

Exclusion Criteria:

  • comorbid autism spectrum disorder
  • comorbid mental retardation
  • lacking the reading and writing skills
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
46 participants (actual)

Study arms

  • Experimental
    CCT+TAU group

    The participants in CCT+TAU group received compensatory cognitive training plus treatment as usual. The CCT intervention consisted of two 50-minute sessions each week for 10 weeks

    Behavioral: Compensatory Cognitive Training

  • No intervention
    TAU group

    The participants in TAU group received usual treatment at the same time as CCT+TAU group.

Interventions

  • BehavioralCompensatory Cognitive Training

    Teach the participants compensatory cognitive skills and strategies

06

What researchers measure

Primary outcomes

  1. Change scores of Rosenberg Self-Esteem Scale (RSES)

    The Chinese version of Rosenberg Self-Esteem Scale (RSES) was implemented as self-esteem measures. The total score ranged from 10 to 40, with higher scores reflecting higher levels of self-esteem.

    Time frame: 3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention

  2. Change scores of General Self-Efficacy Scale (GSES)

    The Chinese version of General Self-Efficacy Scale (GSES) consisted of 10 items, assessing optimistic self-beliefs to cope with a variety of difficult demands in life. The total score ranged from 10 to 40, with higher scores indicating more self-efficacy.

    Time frame: 3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention

  3. Change scores of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4)

    The Chinese version of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) was administered to measure subjective quality of life. The total scores ranged from 33-165, with higher scores indicating comparatively lower quality of life.

    Time frame: 3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention

  4. Change scores of Internalized Stigma of Mental Illness (ISMIS)

    The Chinese version of Internalized Stigma of Mental Illness (ISMIS) consists of 29 items incorporated in five domains: alienation, stereotype endorsement, discrimination experience, social withdrawal, and stigma resistance. The total scores range from 29-116. The higher scores on the ISMIS indicates more severe internalized stigmatization.

    Time frame: 3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention

07

Study locations

1 site
  • Taoyuan Psychiatric Center Ministry of Health and Welfare
    Taoyuan, 330, Taiwan
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jan 2018 to primary completion in May 2018, 4 months.

Of 755 non-industry interventional studies with no phase under Schizophrenia, half reached primary completion within 33 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 56. This study's 4 months is below that.

Counting every sponsor, half of 768 studies reached it within 32 months; a quarter within 16 and three quarters within 55.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 26, 2019
First posted
Aug 1, 2019
StartActual
Jan 5, 2018
Primary completionActual
May 31, 2018
CompletionActual
May 31, 2018
Last update
Aug 1, 2019
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 1, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04040998
Lead sponsor
Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan
Responsible party
YU SHIUAN LIAW (Occupational Therapist, Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan) — Principal investigator
First posted
Aug 1, 2019
Start date
Jan 5, 2018
Primary completion
May 31, 2018
Completion
May 31, 2018
Last update
Aug 1, 2019

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.

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