An interventional study of single-injection TQLB(transmuscular quadratus lumborum block) and Morphine given as IPCA(intravenous patient controlled analgesia) in Laparoscopic Renal Surgery, Pain Management and Nerve Block, sponsored by Cui Xulei. Completed at 1 site in China. Open to participants aged 17 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-11-13.
Sponsored by Cui Xulei · Not applicable, Interventional, and Supportive care
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay，et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic partial nephrectomy.
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's enrollment of 60 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Cui Xulei is the lead sponsor of 10 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Procedure: single-injection TQLB(transmuscular quadratus lumborum block) · Drug: Morphine given as IPCA(intravenous patient controlled analgesia)
postoperative IPCA is given alone
Drug: Morphine given as IPCA(intravenous patient controlled analgesia)
Inject 0.6ml/kg local anesthetics in between quadratus lumborum and psoas major under ultrasound guidance
PCIA was initiated using a pump set to deliver boluses of 1.5-2 mg of morphine with a 5-minute lockout interval and no background infusion. The maximal permitted dosage of morphine was set at 8 mg/h.
cumulative morphine consumption 8 hours after surgery
Time frame: at the 8 hours after surgery
cumulative morphine consumption at other time points after surgery
Time frame: at 0, 2, 4, 12, 24 and 48 hours after surgery
The pain scores(at rest or on activity) determined by the numeric rating scale (NRS, 0-10)
NRS is an internationally recognized pain scale with 11 points ranging from 0 to 10 points, with 0 defined as no pain and 10 defined as the worst pain imaginable.
Time frame: at 0, 2, 4, 8,12, 24, 48 and 72 hours after surgery
episodes of nausea and vomiting
Time frame: within 24 hours after the surgery
ambulation time
time from the end of the surgery to the first time to out-of-bed activity
Time frame: within the 5 days after surgery
time of recovery of bowl movement
time from the end of the surgery to the first time of bowl movement
Time frame: within the 5 days after surgery
patient satisfaction with anesthesia
Patient satisfaction with anesthesia was assessed using a 5-point scale (5: very satisfied; 4: satisfied; 3: neither satisfied nor dissatisfied; 2: dissatisfied; 1: very dissatisfied)
Time frame: at 48 hours after surgery
quality of recovery evaluated by the self-assessment 15-item quality of recovery (QoR) scale
QoR is a 15-item questionnaire which will score on a scale of 0-10 pertaining to patient's comfort, support system, pain, well-being, and ability to carry out daily activities, where 0 indicates none of the time and 10 indicates all of the time
Time frame: at 72 hours and 120 hours after the sugery
postoperative length of hospital stay
time to patient's discharge
Time frame: within 2 weeks after the surgery
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Nov 2019. You cannot join it, but the record below documents what was studied.
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Cui Xulei