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Status unknownNCT03981848Updated Jun 11, 2019

Radiomics-based Non-invasive Classifier Research for HCC-related Liver Transplantation

An observational study in Hepatocellular Carcinoma, Liver Transplantation and Magnetic Resonance Imaging, sponsored by Zhejiang University. Status unknown. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2019-06-11.

Sponsored by Zhejiang University · Observational

The sponsor has not verified this record recently (last verified Jun 2019), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
200
Ages
18 Years to 70 Years
Sex
All
01

Study summary

The purpose of this study is to establish a non-invasive radiomics method to filter high recurrent-risk liver transplantation recipient population

Read the detailed description

Hepatocellular carcinoma is one of the most common malignant tumors in the world with high incidence and mortality. Liver transplantation is the most effective treatment for HCC and is in high demand in China. However, recurrence of HCC among liver transplantation recipients is still a great challenge and threat to the survival of recipients. So it is of great significance to establish a non-invasive way to filter high liver transplantation recipient population before transplantation. Based on large scales of pre-treatment MR images, the investigator's study aims to establish a non-invasive radiomics method to filter high recurrent-risk liver transplantation recipient population. This study will contribute to the precise selection of HCC-related liver transplantation recipients.

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Conditions studied

  • Hepatocellular Carcinoma
  • Liver Transplantation
  • Magnetic Resonance Imaging
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In context

Carcinoma, Hepatocellular

3,182 studies on the registry are indexed under Carcinoma, Hepatocellular; 954 are open to participants now.

This study's planned enrollment of 200 is close to the median of 200 across 754 observational studies indexed under Carcinoma, Hepatocellular.

Browse Carcinoma, Hepatocellular studies →

Lead sponsor

Zhejiang University is the lead sponsor of 351 studies on the registry; 165 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

hospitalization patients

Inclusion criteria

  • All patients had postoperative pathological diagnosis of HCC
  • All patients had underwent contrast-enhanced MRI scan within 2 weeks before liver transplantation

Exclusion criteria

Exclusion Criteria:

  • patients whose pathological diagnosis is not HCC
  • patients whose CT images were affected by strong imaging artifacts, i.e. artifacts obscuring more than 10% of whole volume of interest
  • patients whose clinical data or CT images were missing
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
200 participants (estimated)
Patient registry
No

Groups and cohorts

  • Relapse

    Relapse of tumor within two years after liver transplantation

    Other: Risk model of tumor relapse

  • Non-relapse

    Non-relapse of tumor within two years after liver transplantation

    Other: Risk model of tumor relapse

Interventions

  • OtherRisk model of tumor relapse

    High risk factor model of tumor relapse after liver transplantation

    Also known as: Risk model

06

What researchers measure

Primary outcomes

  1. tumor recurrent status

    Time frame: two years

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 11, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03981848
Lead sponsor
Zhejiang University
Collaborators
Fudan University
Responsible party
Xiao Xu (professor, Zhejiang University) — Principal investigator
First posted
Jun 11, 2019
Start date
Jul 2019 (estimated)
Primary completion
Jul 2021 (estimated)
Completion
Dec 2021 (estimated)
Last update
Jun 11, 2019

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2019. You cannot join it, but the record below documents what was studied.

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