An interventional study of Physical training in Alzheimer Disease, sponsored by University of Genova. Completed at 1 site in Italy. Open to participants aged 80 Years to 90 Years. Per ClinicalTrials.gov, last updated 2019-06-10.
Sponsored by University of Genova · Not applicable, Interventional, and Supportive care
The objective of this study was to examine the effects of exercise training on physical function and biochemical markers in elderly Alzheimer's disease patients.
Alzheimer's disease is a neurodegenerative disease characterized by progressive and irreversible degeneration of nerve cells. The loss of these cells leads to the continuous decline in muscle function with alterations in biochemical and haematological parameters. The objective of this study was to examine the effects of exercise training on physical function and biochemical markers in elderly Alzheimer's disease patients.
3,678 studies on the registry are indexed under Alzheimer Disease; 872 are open to participants now.
This study's enrollment of 20 is below the median of 70 across 2,808 interventional studies indexed under Alzheimer Disease.
Browse Alzheimer Disease studies →University of Genova is the lead sponsor of 33 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Subjects belonging to this arm underwent physical training for three months, twice per week (60 minutes per session).
Other: Physical training
Subjects served as controls.
Physical training for three months, twice per week (60 minutes per session).
Tinetti test
The 3-likert test assesses balance and gait abilities with an individual sitting in an armless chair, rising up, staying standing, turning 360° and then sitting back down. Gait is scored over 12 and balance is scored over 16, totalling 28 points.
Time frame: Approximately 10-15 minutes
Berg Balance Scale
The 14-item 5-likert (from 0 to 4) scale objectively determines a patient's balance ability during a series of predetermined tasks. Scores of each item are summed up: the total score ranges from 0 to 56. The lowest the score the lowest is the level of function, the highest the score the highest is the level of function.
Time frame: Approximately 20 minutes
6-minute walking test
This test is a sub-maximal exercise used to evaluate aerobic capacity and endurance.
Time frame: 6 minutes
Timed up and go test
The test measures abilities of a patient initially in a seated position The patient is then asked to stand up up, walk 3 meters, turn around, walk back to the chair and sit down.
Time frame: Approximately 14 seconds
"Walking While Talking" test
This test is a dual-task test, consisting in walking while reciting the alphabet or alternate letters of the alphabet.
Time frame: Approximately 1 minute
Red blood cell count
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
White blood cell count
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Hemoglobin
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Platelet count
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Hematocrit
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Triglycerides
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Cholesterol
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Total bilirubin
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
AST (aspartate aminotransferase)
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
ALT (alanine aminotransferase)
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Blood pressure
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Creatinine
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Urea
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Glucose
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Sodium
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Calcium
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Potassium
Assessed with routine blood/biochemical assays
Time frame: Approximately 10-15 minutes
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2019. You cannot join it, but the record below documents what was studied.
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University of Genova