An interventional study of Monofilament suture and Multifilament suture in Wound Heal, Cesarean Section Complications and Cesarean Wound Disruption, sponsored by Bezmialem Vakif University. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-02-11.
Sponsored by Bezmialem Vakif University · Not applicable, Interventional, and Prevention
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
Cesarean section (CS) is the most common type of obstetric surgery. When medically justified, CS can effectively prevent maternal and perinatal mortality and morbidity however, there are many short and long-term complications of CS. One of the most common complications is the CS scar defect. CS scar defects can develop after transverse incision of the lower uterine segment, which may result in prolonged postmenstrual bleeding, spotting, pelvic pain, and infertility. Suture material is an essential part of any major surgery, serving to hold opposing tissues together and accelerate the healing process, resulting in decreased scarring of the affected areas. We sought to evaluate the effects of different synthetic absorbable suture materials on cesarean scar defect formation.
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This study's enrollment of 95 is above the median of 52 across 3,239 interventional studies indexed under Wounds and Injuries.
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Exclusion Criteria:
continuous double-layer unlocked suturing with 1.0 monofilament synthetic absorbable suture
Other: Monofilament suture
continuous double-layer unlocked suturing with 1.0 multifilament synthetic absorbable suture
Other: Multifilament suture
1.0 monofilament synthetic absorbable suture for closure of the low transverse uterine incision
1.0 multifilament synthetic absorbable suture for closure of the low transverse uterine incision
The healing ratio
Six months after the operation, the integrity of the cesarean scar at the uterine incision site will be assessed by hydrosonography. The healing ratio will be calculated as the thickness of the residual myometrium covering the defect, divided by the sum of the thickness of the residual myometrium covering the defect and the height of the wedge-shaped defect.
Time frame: 6 months
blood loss
The hemoglobin and hematocrit values will be measured 24 hours after CS
Time frame: 24 hours
additional sutures
number of additional hemostatic sutures
Time frame: 2 hours
This study is completed, as verified in Feb 2020. You cannot join it, but the record below documents what was studied.
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Bezmialem Vakif University