An interventional study of Ultrasound quadratus lumborum block with bupivacaine 25% and lumbar epideural block with bupivacaine 25% in Postoperative Pain and Inflammatory Response, sponsored by Assiut University. Status unknown at 1 site in Egypt. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2019-07-05.
Sponsored by Assiut University · Not applicable, Interventional, and Treatment
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's planned enrollment of 60 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
received pre-emptive ultrasound-guided quadratus lumborum block with 25 mL of 0.25% bupivacaine on each side of the abdominal wall before induction of GA.
Other: Ultrasound quadratus lumborum block with bupivacaine 25%
received pre-emptive lumbar epidural block with 15 mL of 0.25% bupivacaine before induction of GA.
Other: lumbar epideural block with bupivacaine 25%
echogenic needle will be inserted in-plane with the ultrasound beam in a posterior-to-anterior direction through the quadratus lumborum muscle until the ventral fascia of the muscle penetrated. At this point, the needle directed toward the fascial plan between the quadratus lumborum and the Psoas muscle
lumbar epidural will be performed for patients in group II using a 16-gauge Touhy epidural needle by a median approach. The T12 - L1 or L1 - L2 interspaces will be chosen for the injection. The epidural space identified by the loss of resistance technique.
postoperative pain
postoperative pain intensity.
Time frame: first 24 hours postoperatively
postoperative inflammatory response
inflammatory response represented by the levels of: interleukins 1,6, and tumor necrosis factor alpha
Time frame: first 24 hours postoperatively
side effects
sedation, nausea, vomiting, and respiratory depression
Time frame: first 24 hours postoperatively
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.
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Assiut University