An interventional study of Drug: dextrose containing infusion in Perioperative Complication, sponsored by Istanbul University. Completed. Open to participants aged 6 Months to 12 Years. Per ClinicalTrials.gov, last updated 2019-05-20.
Sponsored by Istanbul University · Not applicable, Interventional, and Treatment
Background:Hyperglycemia and hypoglycemia both cause detrimental side effects for pediatric patients. Prolonged fasting time, age dependent physiological diffences and individual differences of patients make complicated the perioperative fluid therapy. Isotonic electrolyte solutions without glucose or with lower glucose concentrations recommended for intraoperative period in pediatric patients.
Objective: The aim of this prospective study is to evaluate the different glucose concentrations(without dextrose, 1 % dextrose+LR, 2 % dextrose+LR) in perioperative infusion solutions according to preoperative blood glucose level to maintain normoglycemia in pediatric patients.
Method: The consecutive 250 eligible pediatric patients aged between 6 months- 12 years with ASA risk score of I-II undergoing surgery lasting less than four hours were enrolled the study in six months period. Patient demographics, procedure, preoperative fasting time, preoperative and postoperative glucose levels were documented. Lactate ringer (LR) solution with % 2 glucose was infused to the patients with preoperative blood glucose level lower than 60 mg/dL, LR solution with % 1 glucose was used for the patients with preoperative blood glucose level between 60-90 mg/dL, LR solution without glucose was used for the patients with preoperative blood glucose level higher than 90 mg/dL.
Lactate ringer (LR) solution with % 2 glucose was infused to the patients with preoperative blood glucose level lower than 60 mg/dL, LR solution with % 1 glucose was used for the patients with preoperative blood glucose level between 60-90 mg/dL, LR solution without glucose was used for the patients with preoperative blood glucose level higher than 90 mg/dL
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İnclusion criteria;
Exclusion Criteria:
Drug: LR infusion LR solution without glucose; the patients with preoperative blood glucose level higher than 90 mg/dL.
Procedure: Drug: dextrose containing infusion
Drug:LR+ 1% Dextrose infusion LR solution with % 1 glucose: the patients with preoperative blood glucose level between 60-90 mg/dL,
Procedure: Drug: dextrose containing infusion
Drug:LR+ 2 % Dextrose infusion Lactate ringer (LR) solution with % 2 glucose; the patients with preoperative blood glucose level lower than 60 mg/dL,
Procedure: Drug: dextrose containing infusion
Drug: infusing dextrose containing or non glucose fluid according to blood glucose level
Also known as: drug: non dextrose containing infusion
glucose level
blood glucose level measurement with finger stick monitoring
Time frame: perioperative period
hyperglysemia or hypoglysemia ratio
blood glucose level measurement with finger stick monitoring
Time frame: perioperative
No study locations are listed for this record.
This study is completed, as verified in May 2019. You cannot join it, but the record below documents what was studied.
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Istanbul University