An interventional study of SMR neurofeedback training to MCI in Mild Cognitive Impairment, sponsored by Fabienne Marlats. Completed. Open to participants aged 65 Years to 90 Years. Per ClinicalTrials.gov, last updated 2019-02-28.
Sponsored by Fabienne Marlats · Not applicable, Interventional, and Prevention
This is a non-pharmacological pilot study showing the improvement of a SMR/theta neurofeedback training program on cognitive performance and EEG activity in Elderly with Mild Cognitive Impairment.
Neurofeedback training (NF) as self-regulation method of brain activity, may be beneficial in elderly with mild cognitive impairment. In this pilot study, the investigators studied whether a sensorimotor(SMR)/theta NF training could improve cognitive performance and brain electrical activity in a sample group of elderly patients with mild cognitive impairment. Twenty participants performed an electroencephalography recording, a battery of neuropsychological tests before the neurofeedback training program (T0), following the neurofeedback training program (T1) and 1-month follow-up (T2).
3,843 studies on the registry are indexed under Cognitive Dysfunction; 1,100 are open to participants now.
This study's enrollment of 20 is below the median of 65 across 2,808 interventional studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →Fabienne Marlats is the lead sponsor of 3 studies on the registry; none are open to participants now.
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A sensorimotor/theta neurofeedback training consisted of 20 individuals sessions, twice a week during 11 weeks maximum. For each subject, NF was planned and conducted by a neuropsychologist experienced in neurophysiology an neurofeedback. Each session lasted 1h10 minutes and was conducted as follows: * Preparation and installation of the electrodes, verification of the impedance, adjustement of the calibration. * NF training (tasks and video described below)(45minutes) * Feedback and debriefing about the session (15 minutes)
Behavioral: SMR neurofeedback training to MCI
The intervention consisted to increase the synaptic strengths and sensitivity within this network. Electroencephalography signals for SMR/theta training was recorded at channel Cz according to the international 10-20 system. Theta rhythm was also recorded and, in this case, SMR was stimulated while theta waves were suppressed.A 32 channels system (EEGDigitrcak Biofeedback plus module, Inc Elmiko Medical) was used for the SMR/theta Neurofeedback training.
Also known as: SMR, neurofeedback
Rey Auditory Verbal Learning test
Assessment of verbal learning in episodic memory, evaluating the ability to encode, combine, store and long-term consolidation process.
Time frame: Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up
Relative power for delta, theta, alpha, sensorimotor and lower beta frequency bands.
Electroencephalography was recorded and EEG power spectrum was calculated using the fast Fourier transform. The power spectral density was calculated to extract the relative power for each frequency band and estimated as a log-ratio.
Time frame: Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.
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