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CompletedNCT03850925Updated Aug 26, 2026

Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars

An interventional study of Laser therapy in Acne Scars, sponsored by Dongtan Sacred Heart Hospital. Completed at 1 site in South Korea. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-26.

Sponsored by Dongtan Sacred Heart Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
25
Allocation
Randomized
Ages
19 Years and older
Sex
All
01

Study summary

This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.

Read the detailed description

This trial is a 17-week, prospective, randomized split-face study that compares the results between two facial sides either receiving the picosecond 1064-nm laser or nonablative fractional laser treatment for atrophic acne scar.

02

Conditions studied

  • Acne Scars
03

In context

Lead sponsor

Dongtan Sacred Heart Hospital is the lead sponsor of 9 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Subjects with facial atrophic acne scars
  • Subjects who observe the schedules and protocols of the clinical trial
  • Subjects who give informed consent to participate in the clinical trial

Exclusion criteria

Exclusion Criteria:

  • Subjects who have active acne under treatment
  • Subjects who had received any other treatments for acne scarring for 6 months prior to the first treatment
  • Subjects who underwent other treatments including chemical, mechanical or laser resurfacing during the study period
  • Subjects who have current acute illness
  • Subjects who are considered inappropriate for the clinical trial under the judgement of investigators
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
25 participants (actual)

Study arms

  • Experimental
    Picosecond laser

    Intervention: four consecutive sessions of 1,064-nm picosecond laser at 3-week intervals

    Procedure: Laser therapy

  • Active comparator
    Fractional laser

    Intervention: four consecutive sessions of nonablative fractional laser at 3-week intervals

    Procedure: Laser therapy

Interventions

  • ProcedureLaser therapy

    4 consecutive sessions of laser therapy

06

What researchers measure

Primary outcomes

  1. Changes in the mean of the ECCA grading scale

    The ECCA (échelle d'évaluation clinique des cicatrices d'acné) grading scale: minimum score 0; maximum score 270; higher values represent a worse outcome.

    Time frame: Week 17

07

Study locations

1 site
  • Dongtan Sacred Heart Hospital, Hallym Universtiy College of Medicine
    Hwaseong-si, Gyeonggi-do 18450, South Korea
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 26, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03850925
Lead sponsor
Dongtan Sacred Heart Hospital
Responsible party
Sponsor
First posted
Feb 22, 2019
Start date
May 1, 2019
Primary completion
Apr 22, 2020
Completion
Apr 22, 2020
Last update
Aug 26, 2026

Study contacts

Gyeong-Hun Park, MD, PhD
principal investigator · Dongtan Sacred Heart Hospital, Hallym University College of Medicine

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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