An observational study in Diabetes, Chronic Kidney Disease and Allergy, sponsored by Universitaire Ziekenhuizen KU Leuven. Completed at 1 site in Belgium. Open to participants aged 2 Years to 85 Years. Per ClinicalTrials.gov, last updated 2020-10-23.
Sponsored by Universitaire Ziekenhuizen KU Leuven · Observational
The purpose of this study is to determine
Chronically ill children
1.1 What is the vaccination status for vaccines recommended by the Superior Health Council in pediatric chronically ill patients (2-16 years of age) who consult within the University hospital of Leuven?
Patients with one of the following chronic conditions will be included:
The vaccination coverage for the following vaccines will be determined:
Timeliness of the vaccines given will also be determined.
1.2 Is the vaccination coverage of pediatric patients (2-16 years of age) comparable to the data on healthy children in 2012?
1.3 What are possible factors that influence coverage in this specific patient populations?
1.4 If the vaccination coverage is too low (below 90-95 percent), what are possbile solutions to increase the coverage rates within this group?
1.5. Determine antibody titers in this same population for the following vaccine-preventable infectious diseases:
1.6 Are antibody titers in this population similar to antibody titers measured in seroprevalence studies of healthy children in the same age group?
2.1 What is the vaccinatiestatus for vaccines recommended by the Superior Health Council of adult patients at risk (over 18 years of age) who consult within the University hospital of Leuven?
Patients with one or more of the following chronic conditions will be included in the study:
The vaccination coverage for the following vaccines will be determined:
2.2 Who immunizes these adult patients at risk?
2.3 What are possible risk factors who influences vaccination status in the adult population?
2.4 If the vaccination coverage is too low (below 90-95 percent), what are possible solutions to improve this coverage in these groups?
2.5 What are the antibody titers measured in the adult risk groups with a chronic condition for the following vaccine-preventable infectious diseases:
2.6 Are antibody titers measured in this population comparable to those of healthy subjects as measured in previous seroprevalence studies?
1,581 studies on the registry are indexed under Cystic Fibrosis; 190 are open to participants now.
This study's enrollment of 2,179 is above the median of 85 across 482 observational studies indexed under Cystic Fibrosis.
Browse Cystic Fibrosis studies →Universitaire Ziekenhuizen KU Leuven is the lead sponsor of 928 studies on the registry; 261 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Chronically ill patients (pediatric and adult) in follow-up at the University Hospital Leuven, Belgium
Exclusion Criteria:
-
Through a questionnaire parents of chronically ill patients will be asked about the vaccination status of all recommended vaccines of their child. Also questions on disease, therapy and sociodemographic factors that can influence vaccination coverage will be asked. A blood sample to determine antibodies against measles, mumps, rubella and pertussis will be drawn from children who consent to sampling. The following groups of patients will be questioned: diabetes, allergy, congenital heart disease, cystic fibrosis, immunodeficiency and transplant patients, cancer patients.
Through a questionnaire chronically ill patients will be asked about their vaccination status of diphtheria, tetanus,pertussis, flu, pneumococcal and hepatitis B vaccine(s). Also questions on disease, therapy and sociodemographic factors that can influence vaccination coverage will be asked. A blood sample to determine antibodies against diphtheria, tetanus and pertussis will be drawn. The following groups of patients will be questioned: diabetes, chronic kidney disease, heart failure, COPD, immunodeficiency and transplant patients, HSCT patients.
Proportion of pediatric chronically ill patients correctly vaccinated with the hexavalent (DTaP-IPV-Hib-HBV), pneumococcal, rotavirus, MMR and MenC vaccine according to the Belgian recommended vaccination schedule.
number of patients vaccinated compared to the entire group
Time frame: 5 years
Proportion of adult chronically ill patients correctly vaccinated diphtheria, tetanus, pneumococci, hepatitis B and influenza according to Belgian recommended vaccination schedule
number of patients vaccinated compared to the entire group
Time frame: 5 years
Proportion of pediatric patients with antibodies against measles, mumps, rubella, diphtheria, tetanus and pertussis in children included in the study and who provided a blood sample
Determination of antibodies against measles, mumps, rubella and pertussis
Time frame: 5 years
Proportion of adult patients with antibodies against diphtheria, tetanus and pertussis.
Determination of antibodies against diphtheria, tetanus and pertussis
Time frame: 5 years
This study is completed, as verified in Oct 2020. You cannot join it, but the record below documents what was studied.
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Universitaire Ziekenhuizen KU Leuven