A Phase 4 interventional study of immediate implant placement with melatonin hyaluronic acid vit C and immediate implant placement without melatonin hyaluronic acid vit C in Immediate Dental Implant, sponsored by Cairo University. Status unknown. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-16.
Sponsored by Cairo University · Phase 4, Interventional, and Treatment
The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies. Since then, many follow-up studies examining different variables have supported the concept of immediate implant placement. pioneered a major contribution to immediate implant placement in human studies which recommended the insertion of an implant into a fresh extraction socket.
They advocated immediate implant placement primarily to reduce the number of surgical interventions needed to perform an implant-supported rehabilitation and shorten the treatment time.
Placement of implants immediately into extraction sites allow the surgeon to idealize the position of the implant appropriately with a better rehabilitation of the normal contour to the facial aspect of the final restoration.
Immediate implant placement in fresh extraction sockets was reported to reduce alveolar bone resorption. Better esthetic outcomes were achieved including the prosthetic crown length in harmony with the adjacent teeth, natural scalloping and easier distinct papillae to achieve and maximum soft tissue support.
Hyaluronic acid is a glycosaminoglycan, this unique molecule is implicated In a variety of biological functions including structural integrity, and the regulation of embryologic development. It is described as a natural organic substance, with physiological therapy activity, main component of the extracellular matrix of many tissues such as the skin, synovial joints and periodontal tissues .
Cairo University is the lead sponsor of 4,909 studies on the registry; 1,445 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion Criteria:
1. Smokers. 2. Systemic disease that may affect the final outcome of the surgical procedure.
3. No or poor patient's compliance. 4. Patients with psychological problems. 5. Pathology at the site of intervention. 6. Pregnant patients. 7. Patients refuse to sign an informed consent.
implant placement with topical application of hyaluronic and melatonin and systemic administration of vitamin C
Procedure: immediate implant placement with melatonin hyaluronic acid vit C
immediate implant placement alone without melatonin or hyauronic acid nor vitamin c
Procedure: immediate implant placement without melatonin hyaluronic acid vit C
immediate implant placement with melatonin and hyaluronic acid and systemic administration vitamin C
Also known as: early implant placement
immediate implant placement without melatonin and hyaluronic acid and systemic administration vitamin C
Also known as: early implant placement
implant stability
implant stability by ostell
Time frame: 6 months
soft tissue healing
soft tissue healing by likert scale (0 indicate complete soft tissue Closure (no line of fibrin) , 1 indicate complete closure (thin line of fibrin) , 2 indcate complete closure (fibrin) , 3 indicate in complete closure (dehiscence ) , 4 indicate incomplete closure (necrosis)
Time frame: 6 months
No study locations are listed for this record.
Plan to share: Undecided — i will check with my study chair
Start is estimated for Feb 2019; primary completion for Feb 2022, 36 months later.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
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