An interventional study of Licorice in Dental Caries, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 25 Years. Per ClinicalTrials.gov, last updated 2022-02-08.
Sponsored by Cairo University · Not applicable, Interventional, and Prevention
The objective is to conduct an RCT to evaluate the effectiveness of Licorice in comparison to standard caries preventive measures for the prevention of new carious lesions in high caries risk patients.
Research hypothesis (Null hypothesis):
The present clinical trial will be conducted to reject or accept the null hypothesis that using Licorice extract mouth wash in addition to standard preventive measures will not differ from using standard preventive measures alone in preventing incidence of new carious lesions.
PICOTS:
P: Population with high caries risk patients
I: Use of licorice.
I2: Use of chlorhexidine
C: Use of standard preventive measures (tooth brushing, tooth paste, interdental cleaning).
O.1: Primary outcome is incidence of new carious lesions
T: Time for measurement is 12 months
S: A Randomized controlled clinical trial (Parallel study)
1,109 studies on the registry are indexed under Dental Caries; 197 are open to participants now.
This study's enrollment of 81 is above the median of 60 across 916 interventional studies indexed under Dental Caries.
Browse Dental Caries studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
licorice is one of the natural products that is listed by the Food and Drug Administration (FDA) as GRAS (generally regarded as safe) when used as food flavoring and sweetening agent which has an antimicrobial, anti-inflammatory and antiviral activity.
Other: Licorice
The "gold standard" of oral therapeutics is Chlorhexidine due to its prolonged broad- spectrum antimicrobial effect.
Other: Licorice
Participants in this group will follow only the standard preventive measures which is brushing twice a day after breakfast and before bed time and daily flossing interdentally before bed time. (No Mouthwash is used)
Natural herbal product
Also known as: Glycyrrhiza glabra Linn, Mulethi
Incidence of new carious lesions
Appearance of new carious lesions within the study duration
Time frame: 12 months
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.
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Cairo University