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CompletedNCT03751605Updated Mar 1, 2023

Indirect Measurement of Respiratory Quotient in Unipulmonary Ventilation.

An observational study in Respiratory Quotient Measurement, sponsored by Centre Hospitalier Universitaire, Amiens. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-03-01.

Sponsored by Centre Hospitalier Universitaire, Amiens · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured respiratory quotient (RQ) from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room.

Unipulmonary ventilation is the rule in thoracic surgery: it improves surgical exposure and protects the operated lung.

However, no study has examined the impact of these mechanisms on the indirect measurement of RQ in unipulmonary ventilation. The main objective of our work is to validate indirect RQ measurement during unipulmonary ventilation. The secondary objective was to assess the predictability of postoperative complications of indirect QR.

02

Conditions studied

  • Respiratory Quotient Measurement

Keywords

  • unipulmonary ventilation, complications, respiratory quotient.
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In context

Lead sponsor

Centre Hospitalier Universitaire, Amiens is the lead sponsor of 582 studies on the registry; 181 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Inclusion Criteria:

  • Age>18 years old
  • Adults admitted to the operating room for thoracic surgery requiring unipulmonary ventilation

Exclusion Criteria:

  • Cardiac surgery
  • Laparoscopy
  • Preoperative oxygen therapy

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age>18 years old
  • Adults admitted to the operating room for thoracic surgery requiring unipulmonary ventilation

Exclusion criteria

Exclusion Criteria:

  • Cardiac surgery
  • Laparoscopy
  • Preoperative oxygen therapy
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (actual)
Patient registry
No

Interventions

  • Procedureunipulmonary ventilation

    observational study based on the computation of respiratory quotient in patient cohort treated by unipulmonary ventilation in routine thoracic surgery

06

What researchers measure

Primary outcomes

  1. Indirect respiratory quotient

    Time frame: during surgery

Secondary outcomes

  1. occurrence of at least one post-operative complication

    the aim is to predict the occurrence of at least one complication with the use of indirect respiratory quotient

    Time frame: through study completion, an average of 6 months

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Study locations

1 site
  • CHU Amiens
    Amiens, 80054, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 1, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03751605
Responsible party
Sponsor
First posted
Nov 23, 2018
Start date
Nov 1, 2018
Primary completion
May 1, 2019
Completion
Feb 1, 2023
Last update
Mar 1, 2023

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.

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