An interventional study of Real rTMS Supplementary motor area and Sham rTMS Supplementary motor area in Vascular Parkinsonism, sponsored by Inje University. Withdrawn at 1 site in South Korea. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by Inje University · Not applicable, Interventional, and Treatment
cannot enroll the participants
Vascular parkinsonism (VP), parkinsonism resulting from ischemic cerebrovascular disease, was suggested in 1929. The main features are wide-based gait, postural instability, and falls, which make patients with VP frustrated. Currently, the treatment is challenging.
Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain, and repetitive transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to explore the therapeutic effect of rTMS for the VP.
Primary outcome
- The number of steps
Secondary outcome
218 studies on the registry are indexed under Parkinsonian Disorders; 63 are open to participants now.
Browse Parkinsonian Disorders studies →Inje University is the lead sponsor of 93 studies on the registry; 1 is open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Real rTMS will be applied over the supplementary motor area
Device: Real rTMS Supplementary motor area
Sham rTMS will be applied over the supplementary motor area
Device: Sham rTMS Supplementary motor area
There will be a series of four rTMS blocks separated by 10 minutes. Each block will consist of 15 to 25 pulse trains of 1-second duration at 25 Hz, with an intertrain interval of 10 seconds.
Also known as: Real repetitive transcranial magnetic stimulation
There will be no real brain stimulation in Sham rTMS, and participant will be blinded.
Also known as: Sham repetitive transcranial magnetic stimulation
Unified Parkinson's Disease Rating Scale (UPDRS) part III-motor part (Number 18 ~31 of UPDRS)
Motor functions will be checked using UPDRS. Each item of the motor part ranges from 0 to 4 (0 means normal, 4 means worst condition). Total sum will be calculated.
Time frame: 2 days
Finger tapping test with right hand
Finger tapping test with right hand, as quickly as possible for 15 second. The total number of taps will be calculated. The test will be twice with one minute interval. After the test performed twice, the average of the tests will be used.
Time frame: 2 days
The total number of steps during the stand-walk-sit (SWS) test
SWS test is Standing up, making a 9 m round trip, and sitting down as quickly as possible. The number of steps will be recorded.
Time frame: 2 days
The completion time during the SWS test
The completion time will be recorded.
Time frame: 2 days
Freezing episodes of gait trajectory
The number of freezing episodes during rapid full turns and dual task
Time frame: 2 days
Patient and Clinical Global Impression Scale
7-point scale that requires the patient (or clinician) to rate the response of the interventions. The rating will be numbered (1: very much improved; 2: much improved; 3: minimally improved; 4: no changes; 5: minimally worse; 6: much worse; 7: very much worse).
Time frame: 2 days
Start is estimated for Dec 2018; primary completion for Dec 2024, 72 months later.
How these figures are worked out, and which studies are left out of them.
cannot enroll the participants
cannot enroll the participants
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is withdrawn, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Inje University