An interventional study of BCAA in Pre-diabetes, Obese and Glucose Intolerance, sponsored by University of California, Los Angeles. Completed at 1 site in United States. Open to participants aged 20 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-20.
Sponsored by University of California, Los Angeles · Not applicable, Interventional, and Treatment
This study aims to determine whether the use of Branched-Chain Amino Acids (BCAA's) regulate insulin and glucagon secretion, and whether the supplement has any effect on body weight and body composition. Subjects who participate in this study will receive an 8-week supply of supplement. The study supplements will be manufactured by Scientific Living, in Irvine, CA for high dose BCAA and the low dose BCAA is manufactured by Nutribiotic, Lakeport, CA. Timed blood collections will be used to measure how BCAA affect glucose metabolism/insulin sensitivity in human subjects.
999 studies on the registry are indexed under Prediabetic State; 238 are open to participants now.
This study's enrollment of 14 is below the median of 65 across 844 interventional studies indexed under Prediabetic State.
Browse Prediabetic State studies →University of California, Los Angeles is the lead sponsor of 1,142 studies on the registry; 192 are open to participants now.
Of its 91 completed or terminated interventional studies of FDA-regulated products, 66 (73%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Subjects will be randomly assigned to take either the 25g supplement (containing 4g BCAA) daily for 4 weeks followed by the 20g BCAA supplement daily for 4 weeks, or vice versa, cross-over design
Dietary Supplement: BCAA
Subjects will be randomly assigned to take either the 25g supplement (containing 4g BCAA) daily for 4 weeks followed by the 20g BCAA supplement daily for 4 weeks, or vice versa, cross-over design
Dietary Supplement: BCAA
Subjects will be randomly assigned to take either the 25g supplement (containing 4g BCAA) daily for 4 weeks followed by the 20g BCAA supplement daily for 4 weeks, or vice versa
Also known as: Branch Chain Amino Acid
Measure of glucose AUC during 2H OGTT (Frame: 10 weeks)
To assess change of glucose AUC during 2H OGTT test
Time frame: Baseline week4, week6 and 10 weeks
Measure of body composition (Time Frame: 10 weeks)
To assess changes in body composition (fat mass, lean body mass in Kg)
Time frame: Baseline week4, week6 and 10 weeks
Plan to share: No
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of California, Los Angeles