An interventional study of Alternate Day Fasting and Exercise in Overweight, Obesity and Diet Modification, sponsored by Gangnam Severance Hospital. Completed. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2018-08-29.
Sponsored by Gangnam Severance Hospital · Not applicable, Interventional, and Prevention
Alternate day fasting is known to be helpful to control weight and have a positive effect on insulin resistance and cardiovascular risk factors. However, there have been no studies on weight reduction program combining alternate day fasting with exercise which preserves lean mass in Korea. The purpose of this randomized clinical trial is to examine the effects of alternate day fasting and exercise on weight reduction, visceral fat, and metabolic parameters in overweight or obese adults.
3,670 studies on the registry are indexed under Overweight; 849 are open to participants now.
This study's enrollment of 100 is above the median of 73 across 3,175 interventional studies indexed under Overweight.
Browse Overweight studies →Gangnam Severance Hospital is the lead sponsor of 141 studies on the registry; 37 are open to participants now.
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Exclusion Criteria:
Behavioral: Alternate Day Fasting · Behavioral: Exercise
Behavioral: Alternate Day Fasting
Behavioral: Exercise
regular eating and exercise habits for 8 weeks
During the 8-week intervention, participants consumed 25% of their daily recommended energy intake (approximately 500 kcal) on each "fast day" (24 h), and consumed food ad libitum on each "feed day" (24 h). The "fast day" and "feed day" were repeated every other day, and the "fast day" occurred 3 days per week.
During the 8-week intervention, participants visited the research center gym at least three times per week and received exercise logs. Each exercise session began with 5 minutes of warm-up and ended with 5 minutes of cool-down. Resistance training was performed using weight training machines, barbells, and dumbbells for 40 minutes. Aerobic exercise was performed on motorized treadmills for 20 minutes.
Change in body weight
body weight (kg)
Time frame: baseline, 8 weeks
Change in visceral fat
visceral fat areas (cm2) measured by fat measurement computed tomography (CT)
Time frame: baseline, 8 weeks
Change in fasting glucose
fasting glucose (mg/dL)
Time frame: baseline, 8 weeks
Change in insulin
insulin (mcIU/mL)
Time frame: baseline, 8 weeks
Change in triglyceride
triglyceride (mg/dL)
Time frame: baseline, 8 weeks
Change in high-density lipoprotein cholesterol (HDL-cholesterol)
HDL-cholesterol (mg/dL)
Time frame: baseline, 8 weeks
Change in low-density lipoprotein cholesterol (LDL-cholesterol)
LDL-cholesterol (mg/dL) calculated using the Friedewald equation
Time frame: baseline, 8 weeks
No study locations are listed for this record.
This study is completed, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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Gangnam Severance Hospital