An observational study in Iron Deficiency Anemia, sponsored by Swiss Federal Institute of Technology. Completed at 1 site in Switzerland. Open to female participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-08-22.
Sponsored by Swiss Federal Institute of Technology · Observational
Iron-deficient anaemic subjects are likely to benefit most from oral iron supplements, but supplementation schedules vary widely in clinical practice, absorption is low and compliance is poor due to mild gastrointestinal side effects. The investigators will compare iron absorption from labeled oral iron doses of 100mg and 200mg administered either on two consecutive days or on alternate days in young anemic women.
1,733 studies on the registry are indexed under Anemia; 246 are open to participants now.
This study's enrollment of 20 is below the median of 200 across 326 observational studies indexed under Anemia.
Browse Anemia studies →Swiss Federal Institute of Technology is the lead sponsor of 152 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Young women with iron-deficiency anemia
Exclusion Criteria:
All subjects will go through two iron absorption study cycles. In one cycle they get 100mg oral iron labeled with stable isotopes on two consecutive and on one alternate day and in another cycle they get 200mg oral iron labeled with stable isotopes on two consecutive and on one alternate day. Half of the subjects start with the 100mg cycle whereas the other half starts with the 200mg cycle.
Other: Iron stable isotope labeled iron(II) sulfate
Administration of oral stable isotope labels using different dosings and different regimens in women with iron deficiency anemia
Fractional and total iron absorption
Fractional and total iron absorption from different supplementation regimens
Time frame: absorption will be measured 14days after the 100mg and 200mg cycle
Serum hepcidin
Serum hepcidin after the administration of different doses and using different regimens
Time frame: right before the administration of an iron dose
Serum EPO
Serum EPO after the administration of different doses and using different
Time frame: right before the administration of an iron dose
Serum ferritin
Determination of iron status
Time frame: right before the administration of an iron dose
Serum TfR
Determination of iron status
Time frame: right before the administration of an iron dose
Serum CRP
Determination of inflammation status
Time frame: right before the administration of an iron dose
Serum AGP
Determination of inflammation status
Time frame: right before the administration of an iron dose
Serum iron
Determination of iron status
Time frame: right before the administration of an iron dose
Total iron binding capacity
Determination of iron status
Time frame: right before the administration of an iron dose
This study is completed, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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Swiss Federal Institute of Technology