An interventional study of [LO-LONG] and [HI-SHORT in Spinal Cord Injury, sponsored by Swiss Paraplegic Research, Nottwil. Terminated at 1 site in Switzerland. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-11-09.
Sponsored by Swiss Paraplegic Research, Nottwil · Not applicable, Interventional, and Treatment
insufficient recruitment
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Among 47 studies in Spinal Cord Injuries by Swiss Paraplegic Research, Nottwil — 8 open to participants now, 8 under way, none of them phase 3. Spinal Cord Injuries · Swiss Paraplegic Research, Nottwil.
Among the 47 studies in Spinal Cord Injuries by Swiss Paraplegic Research, Nottwil, this one is the 18th largest by enrollment of the 24 interventional ones that give a count, is one of 5 that started in 2019, is one of 20 with no phase, and was the 21st registered.
2,026 studies on the registry are indexed under Spinal Cord Injuries; 538 are open to participants now.
Browse Spinal Cord Injuries studies →8 of the 47 studies in Spinal Cord Injuries by Swiss Paraplegic Research, Nottwil are open now, in 3 countries. Recruiting first, the newest first:
Swiss Paraplegic Research, Nottwil · Sites in Switzerland
Ages 18–70
Swiss Paraplegic Research, Nottwil · Sites in Switzerland
Ages 18+
Swiss Paraplegic Research, Nottwil · Sites in Switzerland
Ages 18–75
Swiss Paraplegic Research, Nottwil · Sites in Switzerland
Ages 18+
Swiss Paraplegic Research, Nottwil · Sites in Switzerland
Ages 18+ · Women only
By country, each count listing its studies:
Of the 375 Spinal Cord Injuries studies recruiting now, 166 (44%) set no upper age limit and 158 (42%) stop at 75 or younger; 41 take children under 18; 52 take healthy volunteers.
This study: 18 Years to 75 Years · all sexes · no healthy volunteers.
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47 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 5 started in 2019.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 18 is below the median of 24 across 1,634 interventional studies indexed under Spinal Cord Injuries.
Median enrollment 20 across the 24 interventional studies, 50 across the 23 observational. Of the 37 that completed or were terminated, 1 (3%) have results posted.
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Swiss Paraplegic Research, Nottwil is the lead sponsor of 71 studies on the registry; 8 are open to participants now.
2 of the studies in Spinal Cord Injuries by Swiss Paraplegic Research, Nottwil that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06870331Swiss Paraplegic Research, NottwilThe Effect of Probiotic and Prebiotic Supplementation on Gastrointestinal Health in Individuals With Chronic Spinal Cord Injury | 2027-06 |
| NCT07165353Swiss Paraplegic Research, NottwilVirtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI | 2027-11-30 |
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Among the 47 studies in Spinal Cord Injuries by Swiss Paraplegic Research, Nottwil, from their registry updates:
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The aim of this study is to investigate two different modalities of functional electrical stimulation (FES) leg exercise in patients with spinal cord injury (SCI). The primary outcomes being compared are 1. FES-induced leg aerobic fitness, and 2. FES-induced leg strength. There will be two FES-leg training groups, and sub-acute patients with SCI will be randomised between the groups - high-short [HI-SHORT] and low-long [LO-LONG]. Both groups (n=10 per group) will exercise on the Hasomed RehaStim™ exercise ergometer for 6-8 weeks, three-four times per week (24 therapy sessions). [HI-SHORT] will perform 10 x 2-min of high-intensity interval training with a recovery of 1-2 min between exercise bouts. [LO-LONG] will perform 20+ min of continuous exercise at a low-moderate exercise intensity. Exercise intensity for [HI-SHORT] and [LO-LONG] will be titrated by neuromuscular stimulation characteristics. The primary outcomes will be assessed before training commences and after 6-8 weeks of training has been completed.
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Exclusion Criteria:
High-intensity interval training modality of exercise using FES-evoked leg cycling. Three-four times weekly over 6-8 weeks (24 therapy sessions). The programme is 10 x 2-min exercise intervals with 1-2 min of recovery between intervals. High intensity is achieved by high FES current amplitude (120-150 milliampere, patient dependent)
Other: [HI-SHORT
Low-moderate intensity continuous training modality of exercise using FES-evoked leg cycling. Three-four times weekly over 6-8 weeks (24 therapy sessions). The programme is 20+ min continuous exercise. Lower intensity is achieved by lower FES current amplitude (\< 90-100 milliampere, patient dependent)
Other: [LO-LONG]
Both interventions are different modalities of FES-evoked leg exercise, three-four times per week for 6-8 weeks (24 therapy sessions). The comparator intervention (\[LO-LONG\]) uses 20-40 min (patient state of fitness dependent) of continuous leg exercise of lower intensity.
One intervention (\[HI-SHORT\]) uses a variety of leg exercise interval training of higher intensity for 10 x 2-min intervals.
Aerobic Fitness
Change of Peak Oxygen Uptake - VO2peak (L/min)
Time frame: Day 0 to 6 weeks
Muscle Near Infrared Spectroscopy
Change of resting muscle arterial oxygen saturation (%)
Time frame: Day 0 to 6 Weeks
Strength Fitness
Change of Peak Power Output (Watts)
Time frame: Day 0 to 6 weeks
Muscle Volume
Changes of muscle volume (L)
Time frame: Day 0 to 6 weeks
Muscle Fatigue
Changes of time (sec) until muscle fatigue occurs as defined by fall of Power Output (Watts) to 20% of original value
Time frame: Day 0 to 6 weeks
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2019 to primary completion in Nov 2025, 81 months.
Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 9, 2026: primary completion Dec 2026 → Nov 2025 and completion Dec 2026 → Nov 2026.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
insufficient recruitment
insufficient recruitment
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is terminated, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Swiss Paraplegic Research, Nottwil