An observational study in Cancer Risk, sponsored by University of Colorado, Denver. Recruiting at 6 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-10.
Sponsored by University of Colorado, Denver · Observational
This is not a treatment study. The overall objective is to develop an improved standard of care through studying blood, tissue, biological, etc. samples, that patients have allowed researchers to procure.
The Oncology Research Information Exchange Network (ORIEN) hopes to establish a unique collection of blood, tissue, other biological samples and their associated data (survey data, medical records data, cancer registry data, and other related data) from thousands of patients with cancer or at risk of having cancer. Their hope is to, over time, facilitate new clinical trials, technology, informatics solutions, and personalized medicine to each cancer patient.
University of Colorado, Denver is the lead sponsor of 1,499 studies on the registry; 315 are open to participants now.
Of its 139 completed or terminated interventional studies of FDA-regulated products, 89 (64%) have results posted.
Counted across the registry records on this site, refreshed daily.
All persons who are diagnosed with cancer or at risk for cancer.
Non-English speaking subjects will also be invited to participate in the TCCP study, in accordance with COMIRB's short-form consent use.
Exclusion Criteria:
1. Members of vulnerable populations including neonates (birth to 30 days), children (under age 18), wards of the State, prisoners or those on probation or alternate sentencing, or decisionally challenged (adults or children that are cognitively impaired, incompetent to consent, proxy consent, or consenting in life threatening situations).
Patients with cancer or who are at risk of having cancer who have given consent to have blood, tissue, other biological samples and their associated data (survey data, medical records data, cancer registry data, and other related data) collected and stored for the advancement of medicine.
Procedure: Biospeciman Collection · Other: Survey Assessments · Other: Medical Chart Reviews
Collection of blood, tissue, and other biological samples.
Data taken from patient surveys and assessments, including quality of life.
Data taken directly from the patients' medical charts.
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain patient demographics via surveys and questionnaires.
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain medical histories via surveys and questionnaires.
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain cancer predisposing risk factors via surveys and questionnaires.
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain quality of life care via surveys and questionnaires
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain blood samples from consenting patients.
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain tissue samples from consenting patients
Time frame: Up to 20 years
Improve Standard of Cancer Care
Establish a longitudinal clinical and related data and tissue repository that will contain other biological samples from consenting patients
Time frame: Up to 20 years
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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University of Colorado, Denver