An observational study in Bone and Joint Infection, sponsored by Hospices Civils de Lyon. Status unknown at 1 site in France. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2021-08-30.
Sponsored by Hospices Civils de Lyon · Observational
Optimal surgical therapy (debridement in chronic osteomyelitis; device exchange in patients with chronic prosthetic joint infection [PJI]) could be sometimes non-feasible, especially in the elderly population. Therefore, a medical therapy with oral prolonged suppressive antibiotic therapy (PSAT) seems to be an option to prevent recurrence and prosthesis loosening. Unfortunately, some patients are infected with resistant pathogens for which oral antibiotics are not suitable. Subcutaneous (SC) administration of injectable intravenous antibiotics as PSAT could be a convenient way to limit catheter-related complications and facilitate ambulatory care.
However, there are few data concerning the development of resistance under subcutaneous prolonged treatment with betalactamine.
The aim of this study is is just to constitute a biological collection from samples from the GUT microbiote in patients having a bone or joint infection treated by a suppressive subcutaneous antibiotherapy with betalactamine. Later analysis will be led on those samples to detect the acquisition of resistance or not.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's planned enrollment of 20 is below the median of 240 across 2,136 observational studies indexed under Infections.
Browse Infections studies →Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.
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patients having a bone or joint infection treated by a suppressive subcutaneous antibiotherapy with betalactamine
Exclusion Criteria:
The aim of this study is just to constitute a biological collection from samples from the GUT microbiote in patients having a bone or joint infection treated by a suppressive subcutaneous antibiotherapy with betalactamine. No analysis will be done for instance.
Other: BIOLOGICAL COLLECTION FROM THE GUT MICROBIOTE
collection of saddles
BIOLOGICAL COLLECTION FROM SAMPLES FROM THE GUT MICROBIOTE
The aim of this study is just to constitute a biological collection from samples from the GUT microbiote in patients having a bone or joint infection treated by a suppressive subcutaneous antibiotherapy with betalactamine. No analysis will be done for instance.
Time frame: 36 months
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2021. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon