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CompletedNCT03588637Updated Jul 25, 2022

Real-world Daptomycin Use in Chinese ICUs

An observational study in Daptomycin, Real-world Study and Intensive Care Unit, sponsored by West China Hospital. Completed at 1 site in China. Open to participants aged 1 Year to 100 Years. Per ClinicalTrials.gov, last updated 2022-07-25.

Sponsored by West China Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Other
Enrollment
200
Ages
1 Year to 100 Years
Sex
All
01

Study summary

Analyze the effectiveness and safety of Daptomycin(Jiangsu Hengrui Medicine Co., Ltd) in Gram-positive infections in Chinese Intensive Care Units by using the real-world data platform, https://rws.scccmqc.com. Patients who received at least one dose of Daptomycin between 2016 to 2021 are eligible.

02

Conditions studied

  • Daptomycin
  • Real-world Study
  • Intensive Care Unit
03

In context

Lead sponsor

West China Hospital is the lead sponsor of 483 studies on the registry; 240 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Year to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient who are suspected of Gram-positive infection in the Intensive Care Units.

Inclusion criteria

  • Patient who received at least one dose of daptomycin

Exclusion criteria

Exclusion Criteria:

  • No
05

Study design

Observational model
Other
Time perspective
Other
Enrollment
200 participants (actual)
Target follow-up
30 Days
Patient registry
Yes

Groups and cohorts

  • Study population

    Patient who receive at least one dose of daptomycin

    Other: No intervention

Interventions

  • OtherNo intervention

    No intervention

06

What researchers measure

Primary outcomes

  1. mortality

    death

    Time frame: 30 days

  2. Cure Rate

    clinical and microbiological effectiveness

    Time frame: 30 days

Secondary outcomes

  1. Number of participants with treatment-related adverse events

    organ dysfunction,allergy,creatine kinase levels,eosinophilic pneumonia,etc.

    Time frame: 30 days

07

Study locations

1 site
  • West China Hospital
    Chengdu, Sichuan 610041, China
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 25, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03588637
Lead sponsor
West China Hospital
Responsible party
Xuelian Liao (Principal Investigator, West China Hospital) — Principal investigator
First posted
Jul 17, 2018
Start date
Jun 1, 2018
Primary completion
Jan 1, 2021
Completion
Dec 30, 2021
Last update
Jul 25, 2022

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.

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