CClinicalTrials.gg
Status unknownNCT03564431Updated Sep 17, 2019

The Imaging Genetic Study of Type 2 Diabetes and Depression

An observational study in T2DM, sponsored by Kunming Medical University. Status unknown at 1 site in China. Open to participants aged 30 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-17.

Sponsored by Kunming Medical University · Observational

The sponsor has not verified this record recently (last verified Sep 2019), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
120
Ages
30 Years to 70 Years
Sex
All
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Study summary

To investigate the structural/functional abnormalities and the possible genetic endophenotypes of in the Type 2 Diabetes Patient With Depression.

Read the detailed description

Diabetes and depression are harmful to human health,but they often co-exist.At present, the pathophysiological mechanisms underlying the comorbidity of diabetes and depression are discussed, including hypothalamic-pituitary-adrenal axis dysfunction, inflammation, epigenetics, disturbed circadian rhythms, environmental and behavioral factors,neuroimaging,etc.the purpose of the investigator's study is to investigate the structural/functional abnormalities and the possible genetic endophenotypes of in the Type 2 Diabetes Patient With Depression.

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Conditions studied

  • T2DM

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03

In context

Depression

8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.

This study's planned enrollment of 120 is below the median of 160 across 1,084 observational studies indexed under Depression.

Browse Depression studies →

Lead sponsor

Kunming Medical University is the lead sponsor of 11 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

T2DM and depression patients

Inclusion criteria

conform to type 2 diabetes, depression, diagnostic criteria of unrelated normal controls the han nationality patients; Aged 30 to 70 years of age, gender not limited; The patient or legal guardian have signed informed consent of patients.

Exclusion criteria

Exclusion Criteria:

Magnetic resonance imaging has the contraindication, such as metal implants, claustrophobic, etc.

With severe body diseases, including inflammatory diseases and autoimmune diseases; Current or past history of nervous system disease or brain injury. Merge other severe mental illness or existing psychotic symptoms; Always have a mania, hypomania attack; Has a history of substance abuse; Pregnant women and nursing mothers; Estimated compliance is poorer, not partners; Is being treated for a mental drug therapy, and ECT, TMS; Patients with a body mass index > 35; There are currently no taking corticosteroids, immune regulator, etc. Now or ever did not suffer from patients with other diagnosis to the dsm-iv axis I; Merge the endocrine system disease, thyroid, adrenal gland and pituitary gland diseases, etc.

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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
120 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • controls

    Device: Magnetic resonance

  • T2DM patients

    Device: Magnetic resonance

  • depression patients

    Device: Magnetic resonance

  • T2DM with depression patients

    Device: Magnetic resonance

Interventions

  • DeviceMagnetic resonance

    magnetic resonance spectrum of brain

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What researchers measure

Primary outcomes

  1. the neuroimaging of Type 2 Diabetes and Depression

    the structure and function of Abnormalities in the T2DM Patients

    Time frame: from 2017-12 to 2019-12

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Study locations

1 of 1 sites recruiting
  • Psychiatry department, The 1st Affiliated Hospital of Kunming Medical University
    Kunming, Yunnan 650032, China
    Recruiting
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 17, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03564431
Lead sponsor
Kunming Medical University
Responsible party
Yuqi Cheng (associate professor, Kunming Medical University) — Principal investigator
First posted
Jun 20, 2018
Start date
Dec 1, 2017
Primary completion
Dec 1, 2020 (estimated)
Completion
Dec 1, 2020 (estimated)
Last update
Sep 17, 2019

Study contacts

Li Shi, MD
Contact
shili1026@163.com.cn
8687165324888
Xiufeng Xu, MD
principal investigator · Psychiatry department of KMU

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.

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