An interventional study of Nalbuphine and Flurbiprofen Axetil in Surgery, Anesthesia and Pain, sponsored by Sun Yat-sen University. Completed at 1 site in China. Open to participants aged 16 Years to 75 Years. Per ClinicalTrials.gov, last updated 2018-12-26.
Sponsored by Sun Yat-sen University · Not applicable, Interventional, and Treatment
The purpose of this study is to evaluate the postoperative pain and discomfort using flurbiprofen axetil or nalbuphine administration after orbital decompression under general anesthesia.
To investigate postoperative analgesia achieved with intraoperative administration of intravenous nalbuphine and flurbiprofen axetil in patients undergoing orbital decompression
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's enrollment of 63 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Sun Yat-sen University is the lead sponsor of 1,644 studies on the registry; 602 are open to participants now.
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Exclusion Criteria:
flurbiprofen axetil intraoperative administration 100mg
Drug: Flurbiprofen Axetil
nalbuphine intraoperative administration 0.1mg/kg
Drug: Nalbuphine
flurbiprofen axetil intraoperative administration 100mg and nalbuphine intraoperative administration 0.1mg/kg
Drug: Nalbuphine and Flurbiprofen Axetil
Nalbuphine administration during surgery
Flurbiprofen axetil administration during surgery
Nalbuphine and Flurbiprofen Axetil administration during surgery
Pain after orbital decompression
Pain levels measured using Numerical Rating Scale (NRS) ranging from 0 to 10, where 0 represents no pain and 10 represents the worst pain imaginable ; this scale has been confirmed to be sensitive and reliable.Clinically significant postoperative pain was considered serious pain (NRS score ≥5).
Time frame: 24 hour after recovery
Discomfort after orbital decompression
Discomfort levels were measured using Numerical Rating Scale (NRS) ranging from 0 to 10, where 0 represents no discomfort and 10 represents the worst discomfort; this scale has been confirmed to be sensitive and reliable. Discomfort was defined as "sensation other than pain" and included nausea, vomiting, headache, and dizziness. Clinically significant postoperative discomfort was considered serious discomfort (NRS score ≥5) any time postoperatively.
Time frame: 24 hour after recovery
Plan to share: Undecided
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This study is completed, as verified in Dec 2018. You cannot join it, but the record below documents what was studied.
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Sun Yat-sen University