An observational study in Chest Pain, Acute Coronary Syndrome and Heart Attack, sponsored by Manchester University NHS Foundation Trust. Status unknown at 13 sites in United Kingdom. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2024-05-01.
Sponsored by Manchester University NHS Foundation Trust · Observational
The aim of the study is to assess whether a decision aid that is currently used in hospitals across Greater Manchester to determine how likely it is that a patient has a serious heart problem is still accurate in the pre-hospital environment.
The Investigators will aim to recruit up to 700 participants, aged 18-100, who call 999 with a complaint of chest pain and are subsequently attended by the ambulance service. A blood sample will be taken in the ambulance as well as information about the participant's symptoms, past medical history, physical examination findings and heart tracing findings. The participant will then be transferred to hospital, where another blood sample will be taken. Both of these blood samples will be analysed at a later date for the cardiac marker, troponin.
Participants will then be followed up after 30 days via screening of their clinical records and contacting their GP. The investigators will gather information on the participant's initial admission to hospital, as well as any further hospital admissions and investigations that have occurred within the 30 days since this admission. The information collected will include data on serial cardiac marker testing; other laboratory analyses; length of stay; all imaging investigations and procedures; and details of any haemorrhagic complications.
388 studies on the registry are indexed under Chest Pain; 67 are open to participants now.
This study's planned enrollment of 700 is above the median of 500 across 167 observational studies indexed under Chest Pain.
Browse Chest Pain studies →Manchester University NHS Foundation Trust is the lead sponsor of 139 studies on the registry; 26 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study will recruit patients who have called 999 with a complaint of pain, discomfort or pressure in the chest, who are then attended by an ambulance.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Diagnosis of acute myocardial infarction
Time frame: 30 days
Incident major adverse cardiac events
Time frame: 30 days
Prevalent acute myocardial infarction
Time frame: 30 days
Final diagnosis of participant
Time frame: 30 days
Plan to share: No
This study is status unknown, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Manchester University NHS Foundation Trust →