An observational study in Bariatric Surgery, Sleeve Gastrectomy and Obesity, sponsored by Brigham and Women's Hospital. Active, not recruiting at 1 site in United States. Open to participants aged 22 Years to 62 Years. Per ClinicalTrials.gov, last updated 2025-12-04.
Sponsored by Brigham and Women's Hospital · Observational
Among 37 studies in Obesity by Brigham and Women's Hospital — 6 open to participants now, 14 under way, none of them phase 3. Obesity · Brigham and Women's Hospital.
Among the 37 studies in Obesity by Brigham and Women's Hospital, this one is one of 5 that started in 2021, is one of 4 of another kind, reaches primary completion later than 10 of the 13 other live ones, and was the 20th registered.
11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.
This study's planned enrollment of 44 is below the median of 114 across 2,154 observational studies indexed under Obesity.
Browse Obesity studies →6 of the 37 studies in Obesity by Brigham and Women's Hospital are open now, in 2 countries. Each count lists the studies.
Of the 1,336 Obesity studies recruiting now, 377 (28%) set no upper age limit and 856 (64%) stop at 75 or younger; 168 take children under 18; 491 take healthy volunteers.
This study: 22 Years to 62 Years · all sexes · no healthy volunteers.
The full table on the hub →37 studies; the count open now beside each. This study's row is marked.
First in 1976; this study’s year is marked. 5 started in 2021.
Median enrollment 44 across the 29 interventional studies, 246 across the 8 observational. Of the 19 that completed or were terminated, 12 (63%) have results posted.
Brigham and Women's Hospital is the lead sponsor of 1,267 studies on the registry; 228 are open to participants now.
Of its 116 completed or terminated interventional studies of FDA-regulated products, 65 (56%) have results posted.
2 of the studies in Obesity by Brigham and Women's Hospital that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04820036Brigham and Women's HospitalA Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG) | 2026-12-24 |
| NCT06299644Brigham and Women's HospitalEndoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss | 2027-10 |
Among the 37 studies in Obesity by Brigham and Women's Hospital, from their registry updates:
The purpose of the study is to compare dietary habits after bariatric surgery in patients with poor weight loss versus good weight loss outcomes.
The obesity epidemic is a major public health concern with a significant economic burden in the USA. Bariatric surgery is the most effective and durable weight loss treatment, with long-term cardiometabolic health benefits. Among different types of bariatric procedures, sleeve gastrectomy (SG) has become the most commonly performed in USA. While SG is expected to result in a 50-60% excess weight loss, inter-individual differences in weight loss are large and approximately 25% of patients can be considered poor weight-loss responders who either do not lose a substantial amount of weight or regain the lost weight afterwards. The mechanisms underlying this clinical variation remain unknown and interventions to improve on these outcomes critically lacking. Of interest, altered daily dietary habits are experienced by a substantial proportion of bariatric surgery candidates, raising the question whether such alterations may contribute to inter-individual differences in weight loss success. Therefore, the purpose of the study is to compare dietary habits after bariatric surgery in patients with different weight loss outcomes.
Patients that have undergone sleeve gastrectomy surgery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Sleeve gastrectomy surgery patients will take part in in-laboratory assessment. Based on 1-year post-surgical weight loss, a median split will be done to allocate subjects to one of two groups.
Other: In-laboratory assessment
Sleeve gastrectomy surgery patients will take part in in-laboratory assessment. Based on 1-year post-surgical weight loss, a median split will be done to allocate subjects to one of two groups.
Other: In-laboratory assessment
Participants will stay in the laboratory for two days and one night during which they will complete questionnaires, have blood drawn, and have other measurements taken.
Self-rated hunger
Hunger measured from the visual analogue scale (VAS) questionnaire
Time frame: One day of laboratory protocol
Self-rated appetite
Appetite measured from the visual analogue scale (VAS) questionnaire
Time frame: One day of laboratory protocol
Appetite-regulating hormones
Appetite-regulating hormones from blood samples
Time frame: One day of laboratory protocol
Plan to share: No
No publications or documents are linked to this record.
This study is active, not recruiting, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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