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Status unknownNCT03464513Updated Mar 14, 2018

MSCT Angiography in Bleeding

An interventional study of Multislice CT Angiography in Lower Gastrointestinal Bleeding, sponsored by Assiut University. Status unknown. Per ClinicalTrials.gov, last updated 2018-03-14.

Sponsored by Assiut University · Not applicable, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Mar 2018), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
25
Allocation
Not applicable
Sex
All
01

Study summary

Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum .

Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation that can be challenging to localize and treat .

There are many diseases that may cause lower gastrointestinal bleeding, including angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel disease, ischemic bowel disease, and infectious bowel disease.

Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of patients, bleeding is massive or recurrent, requiring imaging localization and directed therapy.

Read the detailed description

Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as high as 40%if there is hemodynamic instability in patients .

Because of the length of GI tract, the multitude of pathologic processes that can result in GI bleeding, imaging plays a primary role in the diagnosis .

Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding .

MSCTA is being increasingly used because it is a widely available, non-invasive and fast diagnostic technique that allows for the visualization of the entire intestinal tract and its lesions, the identification of the vascularity and possible vascular abnormalities. In addition, this technique does not require preparation in patients with acute bleeding.

02

Conditions studied

  • Lower Gastrointestinal Bleeding
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Patients presenting to assiut university hospital with active lower gastrointestinal bleeding.

Exclusion criteria

Exclusion Criteria:

  • Patients whom are sensitive to contrast. Pregnant women. Patients with renal insufficiency
04

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
25 participants (estimated)

Study arms

  • Other
    Patients with GIT bleeding

    Patients with active lower Gastrointestinal bleeding

    Device: Multislice CT Angiography

Interventions

  • DeviceMultislice CT Angiography

    Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding.

05

What researchers measure

Primary outcomes

  1. MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding.

    Multislice ct angiography

    Time frame: 1 hour

06

Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • Yoon W, Jeong YY, Shin SS, Lim HS, Song SG, Jang NG, Kim JK, Kang HK. Acute massive gastrointestinal bleeding: detection and localization with arterial phase multi-detector row helical CT. Radiology. 2006 Apr;239(1):160-7. doi: 10.1148/radiol.2383050175. Epub 2006 Feb 16. PubMed 16484350 ↗
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Registry details

Key details

Study ID
NCT03464513
Lead sponsor
Assiut University
Responsible party
Mina Gergis Naeem (Principal investigator, Assiut University) — Principal investigator
First posted
Mar 14, 2018
Start date
Apr 1, 2018 (estimated)
Primary completion
Apr 1, 2019 (estimated)
Completion
Apr 1, 2020 (estimated)
Last update
Mar 14, 2018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.

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