An observational study in Spinal Cord Injuries, Depression and Anxiety, sponsored by University of Regina. Completed at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-04-19.
Sponsored by University of Regina · Observational
Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →
Among 203 studies in Spinal Cord Injuries with a site in Canada — 66 open to participants now, 73 under way, 4 of them phase 3. Spinal Cord Injuries · Canada.
Among the 203 studies in Spinal Cord Injuries with a site in Canada, this one is the 18th largest by enrollment of the 25 observational ones that give a count, is one of 12 that started in 2017, is one of 25 observational ones, and was the 80th registered.
2,025 studies on the registry are indexed under Spinal Cord Injuries; 537 are open to participants now.
Browse Spinal Cord Injuries studies →66 of the 203 studies in Spinal Cord Injuries with a site in Canada are open now. Recruiting first, the newest first:
University of Alberta · Sites in Canada
Ages 18+
Dr. B. Catharine. Craven · Sites in Canada
Ages 18–75
University of British Columbia · Sites in Canada
Ages 19+
University of Alberta · Sites in Canada
Ages 18+
University of British Columbia · Sites in Canada
Ages 19+
A study can be open while its sites in Canada have not opened yet or have stopped. Only those recruiting at a site in Canada →
Of the 375 Spinal Cord Injuries studies recruiting now, 166 (44%) set no upper age limit and 158 (42%) stop at 75 or younger; 41 take children under 18; 52 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
203 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 13 · Phase 2 27 · Phase 3 18 · Phase 4 8
First in 1999; this study’s year is marked. 12 started in 2017.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 20 is below the median of 60 across 332 observational studies indexed under Spinal Cord Injuries.
Median enrollment 24 across the 178 interventional studies, 42 across the 25 observational. Of the 109 that completed or were terminated, 13 (12%) have results posted.
This tab as a report to print or save as PDF → With an account.
17 of 203 have an industry lead sponsor. The 10 most frequent:
University of Regina is the lead sponsor of 58 studies on the registry; 23 are open to participants now.
University of Regina has 2 studies filed under Spinal Cord Injuries — fewer than ten, so there is no comparison to draw.
20 of the studies in Spinal Cord Injuries with a site in Canada that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07147296ONWARD Medical, Inc.ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury | 2026-11 |
| NCT06828653Holland Bloorview Kids Rehabilitation HospitalComparing Digitally and Traditionally Made Ankle Foot Orthoses | 2026-12 |
| NCT06691165Glen FosterImproving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy | 2026-12 |
| NCT06807528London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sIntermittent Fasting for Inflammation and Depression in Spinal Cord Injury | 2026-12-30 |
| NCT05103436University of AlbertaElectrical Stimulation for Spasticity in Spinal Cord Injury | 2026-12-31 |
Add all 20 to your calendar (.ics) → With an account.
Among the 203 studies in Spinal Cord Injuries with a site in Canada, from their registry updates:
This tab as a report to print or save as PDF → With an account.
In Canada the prevalence of spinal cord injury (SCI) is approximately 85,556, with incidence rates of traumatic and non-traumatic SCI at 1,785 and 2,286 cases per year, respectively. Common secondary health conditions experienced by individuals with SCI include psychological distress and pain. Appropriate management of these secondary conditions, through a multidisciplinary approach, is imperative as they have been shown to contribute to slower recovery, increased negative outcomes, and greater rates of rehospitalizations and health care utilization. However, resource limitations can restrict the ability of service providers to deliver these integrative biopsychosocial approaches in the community. In Canada over 37% of individuals with SCI expressed a need for emotional counselling; of these, only 43% felt that these needs were met. Transportation can also be a significant issue for persons with SCI, with 87% and 73% respectively expressing a need for short- and long-distance transportation. Guided internet delivered cognitive behavioural therapy (ICBT) program offers an alternative approach for psychosocial service delivery in the community. The program provides online structured self-help modules based on the principles of cognitive behavioural therapy (CBT) in combination with guidance from a coach through weekly emails and telephone calls. ICBT has shown to have a greater reduction in levels of anxiety and depression post treatment compared to a waitlist control group, and these levels were maintained at both 3 and 12 month follow-ups. ICBT was shown to have similar effects to face-to-face CBT. These studies demonstrate that guided ICBT is a safe and effective alternative to face-to-face interventions and it may be beneficial for under serviced populations. Hence, examination of its effectiveness is warranted in the SCI population which faces various psychological and somatic secondary issues. Participants with SCI will receive a 8 week guided ICBT program called the Chronic Conditions Course for persons with SCI. The program is completed over 8 weeks with once a week guidance from a coach. The guided course consists of five lessons, "Do It Yourself" activities, and case vignettes adapted from persons with SCI. The course also provides guidance and resources on other essential skills for persons with SCI, including communicating with health care professional, managing chronic pain, and sleep hygiene. Psychosocial outcomes will be assessed at baseline, 8 weeks, and at 3 months. Data on intervention usage and satisfaction measures will also be examined through a qualitative interview. Caregivers of participants will be asked to complete self-report measures and a qualitative interview regarding their caregiver burden.
Any individual with a spinal cord injury will be recruited through primary care physicians, rehabilitation facilities, and community peer groups.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Persons with spinal cord injury
Behavioral: Guided ICBT for persons with Spinal Cord Injury · Other: Survey
An 8-week guided internet-delivered cognitive behavioural therapy (ICBT) will be delivered to participants who have sustained a spinal cord injury. In addition to the online program, a guide with experience delivering ICBT will provide support by email or telephone once a week. The guide will spend approximately 15 minutes per week/per client.
Caregiver burden and mental health will be assessed through online questionnaires.
Change in depression
Patient Health Questionnaire - 9 Item (PHQ-9). Higher total scores indicate greater severity of depression. Scores range from 0 to 27.
Time frame: baseline, start of each Lesson 2-5, 8 weeks, 3 months
Change in anxiety
Generalize Anxiety Disorder - 7 Item (GAD7). Higher total scores indicate greater severity of anxiety. Scores range from 0 to 21
Time frame: baseline, start of each Lesson 2-5, 8 weeks, 3 months
Change in Caregiver Burden from baseline to 8 weeks (Caregivers of persons with SCI only)
Caregiver burden questionnaire. The tool has 12 items. Total scores ranging from 0 to 18. Higher scores indicate greater burden
Time frame: baseline, 8 weeks
Pain (Persons with SCI only)
International Spinal Cord Injury Pain Basic Data Set v2.0 ISCIPBDS
Time frame: baseline, 8 weeks, 3 months
Pain interference (Persons with SCI only)
Brief Pain Inventory Short Form; BPI-SF
Time frame: baseline, 8 weeks, 3 months
Quality of life (Persons with SCI only)
Spinal Cord Injury Quality of Life Short Form; SCI-QoL-SF
Time frame: baseline, 8 weeks, 3 months
Service usage (Persons with SCI only)
Time frame: baseline, 8 weeks, 3 months
Quality of Life (Caregivers of persons with SCI only)
EQ5D
Time frame: baseline, 8 weeks, 3 months, 6 months, and 1 year follow up
Plan to share: No
Ran from Sep 2017 to primary completion in Dec 2018, 15 months.
Of 124 non-industry observational studies under Spinal Cord Injuries, half reached primary completion within 36 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 74. This study's 15 months is below that.
Counting every sponsor, half of 135 studies reached it within 39 months; a quarter within 16 and three quarters within 78.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Regina