An interventional study of Pretraining and Usual care in Oesophageal Cancer, sponsored by Göteborg University. Completed at 1 site in Sweden. Per ClinicalTrials.gov, last updated 2023-10-02.
Sponsored by Göteborg University · Not applicable, Interventional, and Prevention
Among 30 studies in Esophageal Neoplasms with a site in Sweden — 8 open to participants now, 8 under way, 1 of them phase 3. Esophageal Neoplasms · Sweden.
Among the 30 studies in Esophageal Neoplasms with a site in Sweden, this one is the 7th largest by enrollment of the 19 interventional ones that give a count, is one of 2 that started in 2017, is one of 10 with no phase, and was the 18th registered.
1,873 studies on the registry are indexed under Esophageal Neoplasms; 501 are open to participants now.
Browse Esophageal Neoplasms studies →8 of the 30 studies in Esophageal Neoplasms with a site in Sweden are open now. Recruiting first, the newest first:
University Hospital, Antwerp · Sites in Sweden, Belgium, Denmark and 3 more countries
Region Skane · Sites in Sweden
Karolinska University Hospital · Sites in Sweden
National University Hospital, Singapore · Sites in Sweden, Germany, Japan and 3 more countries
Universitaire Ziekenhuizen KU Leuven · Sites in Sweden, United States, Belgium and 3 more countries
A study can be open while its sites in Sweden have not opened yet or have stopped. Only those recruiting at a site in Sweden →
Of the 387 Esophageal Neoplasms studies recruiting now, 245 (63%) set no upper age limit and 75 (19%) stop at 75 or younger; 19 take children under 18; 36 take healthy volunteers.
This study: all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
30 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 6 · Phase 3 2 · Phase 4 1
First in 1998; this study’s year is marked. 2 started in 2017.
This study's enrollment of 100 is above the median of 58 across 1,347 interventional studies indexed under Esophageal Neoplasms.
Median enrollment 80 across the 19 interventional studies, 1,000 across the 11 observational. Of the 19 that completed or were terminated, 1 (5%) have results posted.
This tab as a report to print or save as PDF → With an account.
1 of 30 have an industry lead sponsor. The 10 most frequent:
Göteborg University is the lead sponsor of 270 studies on the registry; 46 are open to participants now.
Göteborg University has 2 studies filed under Esophageal Neoplasms — fewer than ten, so there is no comparison to draw.
1 of the studies in Esophageal Neoplasms with a site in Sweden that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06115629Phase 3University of Dublin, Trinity CollegeSurveillance After Resection of Oesophageal aNd Gastric Cancer (SARONG-II) Trial | 2026-11 |
Among the 30 studies in Esophageal Neoplasms with a site in Sweden, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
Thoracoabdominal oesophageal resection for cancer is a procedure with high risks for complications, and patients' preoperative status is a crucial factor for outcome. There are only a few studies that evaluate the effect of preoperative intervention, including physical exercises and breathing exercises, after this type of surgery.
The aim of the study is therefore to evaluate the effect of a training intervention before resection of the oesophagus.
One hundred patients scheduled for oesophagus resection according to Ivor-Lewis from five different hospitals in Sweden will be included. The patients will be randomized to an intervention group or a control group. The training intervention starts directly after preoperative radiotherapy and chemotherapy are given and lasts until three months postoperatively.
Intervention includes increased physical activity, strength training and respiratory muscle training.
At inclusion and three months after discharge, the patients will undergo tests of physical function and lung function. In addition, they will fill in questionnaires concerning level of physical function, level of physical activity and quality of life. These questionnaires will also be answered one year after surgery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Increased physical activity daily Daily strength training Daily inspiratory and expiratory muscle training Standard care during hospital stay and continued training after discharge.
Other: Pretraining
Standard care including preoperative information and postoperative breathing exercises and mobilization during hospital stay.
Other: Usual care
Increased physical activity, and daily strength training and breathing exercises.
Preoperative information
6 minutes walk test
Test of physical capacity
Time frame: From inclusion to 3 months postoperatively
Spirometry
Vital capacity
Time frame: From inclusion to 3 months postoperatively
Respiratory muscle strength
Maximal Inspiratory Pressure and maximal expiratory pressure
Time frame: From inclusion to 3 months postoperatively
Hand strength
Hand strength (Jamar)
Time frame: From inclusion to 3 months postoperatively
Leg strength- calf strength
Heel rise test
Time frame: From inclusion to 3 months postoperatively
Leg strength
Chair stands test
Time frame: From inclusion to 3 months postoperatively
Rib cage range of motion
Chest excursion and Respiratory Movement Measurement Instrument
Time frame: From inclusion to 3 months postoperatively
Level of physical activity
Scale by Grimby and Frändin
Time frame: From inclusion to 1 year postoperatively (The whole study period)
Physical function
Disability Rating Index
Time frame: From inclusion to 1 year postoperatively (The whole study period)
Postoperative recovery
The Postoperative Recovery Profile
Time frame: From surgery to 1 year postoperatively
Pain in the ribcage
Numeric rating scale, Scale from 0-10 where 0 indicates no pain and 10 worst imaginable pain
Time frame: From inclusion to 1 year postoperatively (The whole study period)
Generic Quality of life
EORTC 3 modules
Time frame: From inclusion to 1 year postoperatively (The whole study period)
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Dec 2017 to primary completion in Dec 2022, 60 months.
Of 209 non-industry interventional studies with no phase under Esophageal Neoplasms, half reached primary completion within 46 months of starting (the median), counting those still running; a quarter within 23 and three quarters within 96. This study's 60 months is above that.
Counting every sponsor, half of 218 studies reached it within 46 months; a quarter within 23 and three quarters within 96.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2023. You cannot join it, but the record below documents what was studied.
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