ClinicalTrials.gg
RecruitingNCT03449472Updated Jul 8, 2026

Bariatric Surgery and Pharmacokinetics of Quetiapine

An observational study in Obesity, Morbid, sponsored by Norwegian University of Science and Technology. Recruiting at 1 site in Norway. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-07-08.

Sponsored by Norwegian University of Science and Technology · Observational

From the registry’s dates

  • Started Jan 2018; still recruiting 8 years 10 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
12
Ages
18 Years to 70 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 33 studies in Obesity, Morbid by Norwegian University of Science and Technology — 21 open to participants now, 21 under way, none of them phase 3. Obesity, Morbid · Norwegian University of Science and Technology.

Planned enrollment
2nd of 26
12 · median 12
Started
2018
with 4 others
Observational
26 of 33
21 open now
Primary completion
2026-10
later than 1 of 20 live
Registered
12th of 33
by date

Among the 33 studies in Obesity, Morbid by Norwegian University of Science and Technology, this one is the 2nd largest by planned enrollment of the 26 observational ones that give a count, is one of 5 that started in 2018, is one of 26 observational ones, reaches primary completion later than 1 of the 20 other live ones, and was the 12th registered.

Obesity, Morbid

941 studies on the registry are indexed under Obesity, Morbid; 163 are open to participants now.

Browse Obesity, Morbid studies →

Open to participants now

21 of the 33 studies in Obesity, Morbid by Norwegian University of Science and Technology are open now, in 1 country. Recruiting first, the newest first:

15 more — sign in →

By country, each count listing its studies:

All 21 open studies →

Where they have run

Who these studies take

Of the 109 Obesity, Morbid studies recruiting now, 21 (19%) set no upper age limit and 83 (76%) stop at 75 or younger; 8 take children under 18; 9 take healthy volunteers.

This study: 18 Years to 70 Years · all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

Was this useful?
Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 33 studies in Obesity, Morbid by Norwegian University of Science and Technology, or all of them as a file.
02

Study summary

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on quetiapine are investigated.

03

Conditions studied

  • Obesity, Morbid

Browse trials for

Keywords

  • Bariatric surgery
  • Gastrointestinal tract
  • Biological availability
  • Pharmacokinetics
  • Quetiapine fumarate
04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients referred for bariatric surgery (gastric bypass or sleeve gastrectomy)

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
  • Being a Norwegian citizen

Exclusion criteria

Exclusion Criteria:

  • Having previously undergone resections in the GI-tract
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
12 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Interventions

  • Patients are tested for their normal prescription quetiapine medication

    Also known as: Quetiapine fumarate

06

What researchers measure

Primary outcomes

  1. Quetiapine concentration in blood serum (area under curve (AUC))

    Time frame: From baseline to 1 year postoperatively

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jan 2018 (actual). Primary completion is estimated for Oct 2026, 105 months after the start.

Of 137 non-industry observational studies under Obesity, Morbid, half reached primary completion within 46 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 132. This study's planned 105 months is above that.

Counting every sponsor, half of 138 studies reached it within 46 months; a quarter within 16 and three quarters within 132.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 22, 2018
First posted
Feb 28, 2018
StartActual
Jan 2, 2018
Primary completionEst.
Oct 2026
CompletionEst.
Oct 2026
Last update
Jul 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03449472
Collaborators
St. Olavs Hospital, Volvat Medisinsk Senter Stokkan, Namsos Hospital, Alesund Hospital
Responsible party
Sponsor
First posted
Feb 28, 2018
Start date
Jan 2, 2018
Primary completion
Oct 2026 (estimated)
Completion
Oct 2026 (estimated)
Last update
Jul 8, 2026

Study contacts

Magnus Strømmen, MSc
Contact
magnus.strommen@stolav.no
0047 72829970
Magnus Strømmen, MSc
principal investigator · St. Olavs Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion