An observational study in Residence or Prolonged Visit at High Altitude as the Cause of Mountain Sickness, sponsored by Tibetan Traditional Medical College. Status unknown at 1 site in China. Open to participants aged 30 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-02-27.
Sponsored by Tibetan Traditional Medical College · Observational
This ambispective cohort study aims to evaluate the effect of high altitudes environment on human's physiological and metabolic markers, specific markers of main human systems, and incidence rate and severity of chronic mountain sickness (CMS).
Qinghai-Tibet plateau is a high altitudes area with average 3,000-5,000 meters height in China. As the partial pressure of oxygen in inspired air falls with increasing terrestrial elevation above sea level, many physiological variables in human body could be affected by this hypobaric hypoxic environment. Up to date, there are no large scale clinical trials assessing these changes in chinese population. The study here would like to provide the newest medical information on the changes of physiological variables and correlation between specific risk factors in chinese adults living at high altitudes for work purpose.
The study population is adults who live at Qinghai-Tibet Plateau for Work Purpose.
Exclusion Criteria:
Qinghai-Tibet Plateau is a high altitude area in which human would be exposed in chronic hypoxia environment.
Other: Chronic hypoxic environment
Chronic hypoxic environment. Since the partial pressure of oxygen in inspired air falls with increasing terrestrial elevation above sea level, many physiological variables in adults would be affected by the chronic hypoxia environment.
Change in weight from baseline at first year
Time frame: Baseline and 1st year
Change in blood pressure as measured by sphygmomanometer from baseline at first year
The blood pressure will be described in the format of diastolic pressure/systolic pressure, and the unit of measure is mmHg.
Time frame: Baseline and 1st year
Change in serum lipid from baseline at first year
Time frame: Baseline and 1st year
Change in blood glucose from baseline at first year
Time frame: Baseline and 1st year
Change in weight from baseline at second year
Time frame: Baseline and 2nd year
Change in weight from baseline at third year
Time frame: Baseline and 3rd year
Change in blood pressure as measured by sphygmomanometer from baseline at second year
The blood pressure will be described in the format of diastolic pressure/systolic pressure, and the unit of measure is mmHg.
Time frame: Baseline and 2nd year
Change in blood pressure as measured by sphygmomanometer from baseline at third year
The blood pressure will be described in the format of diastolic pressure/systolic pressure, and the unit of measure is mmHg.
Time frame: Baseline and 3rd year
Change in serum lipid from baseline at second year
Time frame: Baseline and 2nd year
Change in serum lipid from baseline at third year
Time frame: Baseline and 3rd year
Change in blood glucose from baseline at second year
Time frame: Baseline and 2nd year
Change in blood glucose from baseline at third year
Time frame: Baseline and 3rd year
Pathological changes from baseline at first year in human body systems
Time frame: Baseline and 1st year
Pathological changes from baseline at second year in human body systems
Time frame: Baseline and 2nd year
Pathological changes from baseline at third year in human body systems
Time frame: Baseline and 3rd year
The incidence rate and severity of chronic mountain sickness (CMS)
The diagnosis and severity of CMS is identified and assessed using "The Qinghai Chronic Mountain Sickness Score". The score ranges from 0 to 27, and a higher value means a worse outcome.
Time frame: The 2nd year
The incidence rate and severity of chronic mountain sickness (CMS)
The diagnosis and severity of CMS is identified and assessed using "The Qinghai Chronic Mountain Sickness Score". The score ranges from 0 to 27, and a higher value means a worse outcome.
Time frame: The 3rd year
Relationship between altitudes and pathological changes in human body under chronic hypoxic environment
Time frame: Up to the 3rd year
Relationship between age and pathological changes in human body under chronic hypoxic environment
Time frame: Up to the 3rd year
Relationship between gender and pathological changes in human body under chronic hypoxic environment
Time frame: Up to the 3rd year
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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