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CompletedNCT03443375Updated Feb 23, 2018

Exercise Periodization and Older Adults

An interventional study of Physical exercise in Aging, Physical Activity and Sarcopenia, sponsored by University of Campinas, Brazil. Completed. Open to female participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-02-23.

Primary conditionSarcopeniaRegistry: Motor ActivityReclassifiedWhy we changed it
Registry
Motor Activity — the first condition term the registry derived for this study.
ClinicalTrials.gg
Sarcopenia
Why
  1. Motor Activity is a broad heading, used only when no more specific condition is named.
  2. The study's listed conditions name Sarcopenia.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by University of Campinas, Brazil · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 3 years 1 month after the study started (first participant enrolled Jan 2015, registered Feb 2018).
Phase
Not applicable
Study type
Interventional
Enrollment
14
Allocation
Randomized
Ages
60 Years and older
Sex
Female
01

Study summary

The present study aimed at investigating the effects of two different resistance training protocols - nonperiodized (NP) and daily undulating periodization (DUP) - on hemodynamic, morphofunctional and cognitive parameters of robust older women. Methods: Forty-two older women were randomized allocated into one of the three experimental groups: NP, DUP, and control group (CG). Evaluations of the hemodynamic, morphofunctional and cognitive parameters occurred before, during and after six months. The exercise groups performed the program of exercise twice a week over 22 weeks. In NP, the two weekly sessions were based on 3 sets of 8-10 repetitions at a difficult intensity. However, in DUP, a power exercise session based on 3 sets of 8-10 repetitions at a moderate intensity was added in the first session of the week.

02

Conditions studied

  • Aging
  • Physical Activity
  • Sarcopenia
  • Cognitive Decline
  • Blood Pressure
  • Physical Disability

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Keywords

  • Older adults
  • Physical function
  • Muscle mass
  • Short-term memory
  • Executive function
  • Blood Pressure
  • Resistance training
  • Exercise training
  • Periodization
03

In context

Sarcopenia Reclassified

1,329 studies on the registry are indexed under Sarcopenia; 420 are open to participants now.

This study's enrollment of 14 is below the median of 60 across 855 interventional studies indexed under Sarcopenia.

Browse Sarcopenia studies →

Lead sponsor

University of Campinas, Brazil is the lead sponsor of 168 studies on the registry; 12 are open to participants now.

Browse University of Campinas, Brazil studies →

Compared within Sarcopenia, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Motor Activity. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
60 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Aged ≥60 years;
  • Female;
  • Not having been part of a systematic program of physical exercises in the last 6 months;
  • MEEM score >19 points;
  • Kihon checklist score >10 points;
  • Capacity to perform the basic and instrumental activities of daily living according to Katz and Pfeffer indexes;
  • Self-reported good memory;
  • Complete all measurements.

Exclusion criteria

Exclusion Criteria:

  • Changes on antihypertensive medication in the past 6 months prior to inclusion in the study;
  • Cardiovascular disease (i.e., acute myocardial infarction, stroke, peripheral arterial disease, and transient ischemic disease)
  • Metabolic disease (i.e., diabetes mellitus type I or II), pulmonary disease (i.e., emphysema)
  • Neurological and/or psychiatric disease (i.e., Parkinson's or Alzheimer's disease)
  • Skeletal muscle disorders
  • Comorbidities associated with greater risk of falls
  • Recent history of smoking or alcohol abuse
  • Hormone replacement therapy and/or psychotropic drugs.
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
14 participants (actual)

Study arms

  • Experimental
    Nonperiodized resistance training

    The Nonperiodized group performed was an intervention based on resistance exercise program with a constant intensity.

    Other: Physical exercise

  • Experimental
    Daily undulating periodized

    The Daily undulating periodized program was an intervention based on daily alterations on exercise load. .

    Other: Physical exercise

  • No intervention
    Control group

    The control group remained their regular habits of life during all study period, without engaging in physical exercise programs.

Interventions

  • OtherPhysical exercise

    The interventions proposed in the present trial were based on a safe and well-established exercise training program

06

What researchers measure

Primary outcomes

  1. Changes in transfer capacity in seconds

    TUG performance

    Time frame: 6 months

Secondary outcomes

  1. Changes in fat-free mass in kg

    Fat-free mass

    Time frame: 6 months

  2. Changes in overall cognitive capacity in points

    MEEM

    Time frame: 6 months

  3. Changes in blood pressure in mmHg

    Blood Pressure

    Time frame: 6 months

  4. Changes in shor-term memory in points

    Memory

    Time frame: 6 months

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Coelho-Junior HJ, Goncalves IO, Camara NOS, Cenedeze MA, Bacurau RF, Asano RY, Santana J, Caperuto E, Uchida MC, Rodrigues B. Non-periodized and Daily Undulating Periodized Resistance Training on Blood Pressure of Older Women. Front Physiol. 2018 Nov 27;9:1525. doi: 10.3389/fphys.2018.01525. eCollection 2018. PubMed 30542289 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jan 2015 to primary completion in Dec 2015, 11 months.

Of 492 non-industry interventional studies with no phase under Sarcopenia, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 34. This study's 11 months is below that.

Counting every sponsor, half of 503 studies reached it within 18 months; a quarter within 8 and three quarters within 34.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 8, 2018
First posted
Feb 23, 2018
StartActual
Jan 2015
Primary completionActual
Dec 2015
CompletionActual
Dec 2015
Last update
Feb 23, 2018
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 23, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03443375
Lead sponsor
University of Campinas, Brazil
Responsible party
Hélio José Coelho Júnior (Mr. Coelho-Junior, University of Campinas, Brazil) — Principal investigator
First posted
Feb 23, 2018
Start date
Jan 2015
Primary completion
Dec 2015
Completion
Dec 2015
Last update
Feb 23, 2018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.

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Discussion

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