A Phase 1 interventional study of preoperative localization of SLN detected by CTLG by either methods in Breast Cancer, sponsored by Mansoura University. Status unknown at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2018-02-23.
Sponsored by Mansoura University · Phase 1, Interventional, and Diagnostic
A question is raised about the possibility of accurate localization of the SLN (sentinel lymph node) detected by CTLG (Computed Tomography Lymphography) which offers a detection rate of 100% in many studies In Oncology center, Mansoura University (OCMU), the surgical oncology unit had a previous experience in using charcoal for localization of non-palpable suspicious breast lesions and it showed promising results in comparison to traditional localization methods In addition, we had another study using silver wire for localization of breast masses before neoadjuvant therapy.
In the study, the investigators will study the usage of both methods as preoperative localization methods for the SLN detected by CT lymphography in breast cancer patients The investigators suppose that this method can offer two main advantages over the traditional SLN intraoperative methods which are; saving operative time needed for the intraoperative procedure as well as solving the problem of the need for complex logistic preparations especially for the usage of radioisotope method.
12,815 studies on the registry are indexed under Breast Neoplasms; 2,920 are open to participants now.
This study's planned enrollment of 50 is below the median of 72 across 9,494 interventional studies indexed under Breast Neoplasms.
Browse Breast Neoplasms studies →Mansoura University is the lead sponsor of 1,114 studies on the registry; 185 are open to participants now.
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Exclusion Criteria:
Unfit patients for general anaesthesia
Device: preoperative localization of SLN detected by CTLG by either methods
Device: preoperative localization of SLN detected by CTLG by either methods
50 patients with node negative early breast cancer. The patients were randomized into two groups; SLN localized using CTLG guided injection of liquid charcoal suspended solution (first group) or by placing a 3 cm silver wire using spinal needle (second group). For every patient, SLN biopsy was performed using the traditional method with blue dye. Then dual search for the SLN localized by both the novel \& traditional method was performed.
detection of the sentinel lymph node by the novel method & matching between the sentinel lymph node detected by the novel method and the control one
Time frame: one year
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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