An interventional study of Hypoxia in Baro-reflex Sensitivity, Heart Rate Variability and EEG, Microstates, sponsored by Fliegerärztliches Institut. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-02-15.
Sponsored by Fliegerärztliches Institut · Not applicable, Interventional, and Other
Among 41 studies in Hypoxia with a site in Switzerland — 12 open to participants now, 17 under way, none of them phase 3. Hypoxia · Switzerland.
Among the 41 studies in Hypoxia with a site in Switzerland, this one is the 21st largest by enrollment of the 37 interventional ones that give a count, is one of 3 that started in 2018, is one of 31 with no phase, and was the 13th registered.
1,076 studies on the registry are indexed under Hypoxia; 213 are open to participants now.
This study's enrollment of 20 is below the median of 45 across 769 interventional studies indexed under Hypoxia.
Browse Hypoxia studies →12 of the 41 studies in Hypoxia with a site in Switzerland are open now.
A study can be open while its sites in Switzerland have not opened yet or have stopped. Only those recruiting at a site in Switzerland →
Of the 125 Hypoxia studies recruiting now, 53 (42%) set no upper age limit and 45 (36%) stop at 75 or younger; 15 take children under 18; 33 take healthy volunteers.
This study: 18 Years to 40 Years · all sexes · healthy volunteers too.
The full table on the hub →41 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 1 · Phase 2 3 · Phase 3 1 · Phase 4 2
First in 2008; this study’s year is marked. 3 started in 2018.
Median enrollment 24 across the 37 interventional studies, 42 across the 4 observational. Of the 20 that completed or were terminated, 1 (5%) have results posted.
None of the 41 has an industry lead sponsor. The 10 most frequent:
Fliegerärztliches Institut is the lead sponsor of 2 studies on the registry; none are open to participants now.
Fliegerärztliches Institut has 2 studies filed under Hypoxia — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 41 studies in Hypoxia with a site in Switzerland, from their registry updates:
Nothing recorded among them since 2026-09-25.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different normobaric and hypobaric hypoxic conditions.
Subjects will bike at 1W/kg for 6 minutes at different simulated altitude level in the hypobaric chamber at the FAI in Dübendorf. Concentration performance also will be measured to better understand how hypobaric and hypoxia conditions may affect physiological responses, cerebral and cognitive functions.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
No drug use for this study. No arm used in this study. Subjects are exposed to hypoxic conditions (clinical study).
Other: Hypoxia
Subject will conduct low-intensity exercise on a bike in different hypoxic conditions.
Also known as: Low-intensity cycling exercise
Baro-reflex sensitivity
To test the strength of relationship between RR interval and systolic blood pressure in human. Measurement before and after low intensity exercise in each condition.
Time frame: 6 minutes per record.
Concentration performance
Subjects will conduct a concentration test in each condition.
Time frame: 4 minutes per test
EEG microstates
Microstates analysis to investigate how electrical cerebral activity is affected at rest in hypoxia and influenced by low intensity cycling exercise.
Time frame: 6 minutes per record
Heart rate variability (HRV)
To investigate about stress (sympathetic and parasympathetic activation) in each condition tested.
Time frame: 6 minutes per record
Cerebral blood flow
Regulation of cerebral blood flow in hypoxia at rest and during low-intensity exercise. Measurement before, during and after low intensity exercise in each condition. 6 minutes recording per measurement.
Time frame: 6 minutes per record.
Plan to share: No
No publications or documents are linked to this record.
Ran from Mar 2018 to primary completion in Feb 2019, 10 months.
Of 321 non-industry interventional studies with no phase under Hypoxia, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 27. This study's 10 months is below that.
Counting every sponsor, half of 351 studies reached it within 12 months; a quarter within 3 and three quarters within 27.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.
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Fliegerärztliches Institut