CClinicalTrials.gg
CompletedNCT03435783Updated Apr 23, 2019Results posted

Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing

An interventional study of Brief Electronic Intervention and Attention-Matched Control in HIV Infections and Alcohol Abuse, sponsored by Brown University. Completed at 1 site in United States. Open to male participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-04-23.

Sponsored by Brown University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years and older
Sex
Male
01

Study summary

The overall objective of this research is to use both qualitative and quantitative data to inform the development of a technology-based intervention for heavy drinking and sexual risk behavior among men who have sex with men (MSM) who are seeking free HIV testing. Investigators will be conducting a randomized-controlled pilot test of the intervention among MSM seeking HIV testing in community-based settings to explore its potential impact on alcohol and HIV-related behavioral outcomes. This research will ultimately produce a combined, theory-based, and technology- delivered intervention for heavy drinking and sex risk that is fully portable and has been preliminarily tested for efficacy in community settings where high-risk MSM engage with prevention services.

02

Conditions studied

  • HIV Infections
  • Alcohol Abuse

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03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  1. Biologically male
  2. Aged 18 or older
  3. Fluent English speaker
  4. Unprotected anal sex with a casual male partner at least once in the past 3 months
  5. Heavy alcohol use during the past 2-weeks (>14 drinks per week, or at least one occasion of 5+ drinks on a given occasion)
  6. Breath alcohol concentration (BrAC) of .000 at the time of enrollment
  7. No history of complex alcohol withdrawal
  8. HIV-negative

Exclusion criteria

Exclusion Criteria:

  1. Individuals who are HIV-positive
  2. Individuals who participated in other phases of the research
  3. Individuals who report being coerced to participate
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Single group
Masking
Single (Investigator)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Intervention

    Behavioral: Brief Electronic Intervention

  • Active comparator
    Attention-matched control

    Behavioral: Attention-Matched Control

Interventions

  • BehavioralBrief Electronic Intervention

    The brief electronic intervention will allow users to receive normative feedback based on their alcohol use and sexual activity. Users who show interest in changing their behavior will also be asked to create a plan to do so.

  • BehavioralAttention-Matched Control

    Participants will view a video clip on general health promotion that is a similar length as the intervention arm.

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What researchers measure

Primary outcomes

  1. Number of New Sex Partners, Past 30 Days

    Assessed via self-report using Timeline Follow Back (TLFB)

    Time frame: Past 30 days

  2. Number of Condomless Anal Sex Events, Past 30 Days

    Assessed via self-report using Timeline Follow Back (TLFB); count of the number of such events.

    Time frame: Past 30 days

  3. Number of Drinking Days, Past 30 Days

    Assessed via self-report using Timeline Follow Back (TLFB); count of the average number of drinking days in the past 30

    Time frame: Past 30 days

  4. Number of Heavy Drinking Days (5 or More), Past 30 Days

    Assessed via self-report using Timeline Follow Back (TLFB); count of the number of days.

    Time frame: Past 30 days

  5. Average Number of Drinks Per Drinking Day

    Assessed using Timeline Follow Back (TLFB)

    Time frame: Past 30 days

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Results

Posted Apr 23, 2019

Participant flow

Participant flow — Overall Study
MilestoneStandard Post-test Counseling (Control)Brief Web-based Intervention
Started2020
Completed2019
Not completed01

Outcome measures

PrimaryNumber of New Sex Partners, Past 30 Days

Assessed via self-report using Timeline Follow Back (TLFB)

Time frame:
Past 30 days
Reported as:
Mean · New partners
Number of New Sex Partners, Past 30 Days
New partnersStandard Post-test Counseling (Control)Brief Web-based Intervention
Number of New Sex Partners, Past 30 Days2.53 ± 3.61.37 ± 1.2
PrimaryNumber of Condomless Anal Sex Events, Past 30 Days

Assessed via self-report using Timeline Follow Back (TLFB); count of the number of such events.

Time frame:
Past 30 days
Reported as:
Mean · Events
Number of Condomless Anal Sex Events, Past 30 Days
EventsStandard Post-test Counseling (Control)Brief Web-based Intervention
Number of Condomless Anal Sex Events, Past 30 Days1.06 ± 1.61.08 ± 1.3
PrimaryNumber of Drinking Days, Past 30 Days

Assessed via self-report using Timeline Follow Back (TLFB); count of the average number of drinking days in the past 30

Time frame:
Past 30 days
Reported as:
Mean · Days
Number of Drinking Days, Past 30 Days
DaysStandard Post-test Counseling (Control)Brief Web-based Intervention
Number of Drinking Days, Past 30 Days10.8 ± 6.97.04 ± 5.0
PrimaryNumber of Heavy Drinking Days (5 or More), Past 30 Days

Assessed via self-report using Timeline Follow Back (TLFB); count of the number of days.

Time frame:
Past 30 days
Reported as:
Mean · Days
Number of Heavy Drinking Days (5 or More), Past 30 Days
DaysStandard Post-test Counseling (Control)Brief Web-based Intervention
Number of Heavy Drinking Days (5 or More), Past 30 Days3.83 ± 3.62.67 ± 1.8
PrimaryAverage Number of Drinks Per Drinking Day

Assessed using Timeline Follow Back (TLFB)

Time frame:
Past 30 days
Reported as:
Mean · Drinks
Average Number of Drinks Per Drinking Day
DrinksStandard Post-test Counseling (Control)Brief Web-based Intervention
Average Number of Drinks Per Drinking Day4.73 ± 2.34.54 ± 1.6

Adverse events

Collected over 3 months (the duration of the study period for all participants).. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Standard Post-test Counseling (Control)0/20 (0%)0/20 (0%)0/20 (0%)
Brief Web-based Intervention0/20 (0%)0/20 (0%)0/20 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(Years)InterventionAttention-matched ControlTotal
Mean27.7 ± 8.328.8 ± 9.928.3 ± 9.1
Sex: Female, Male
Sex: Female, Male(Participants)InterventionAttention-matched ControlTotal
Female000
Male202040
Ethnicity (NIH/OMB)
Ethnicity (NIH/OMB)(Participants)InterventionAttention-matched ControlTotal
Hispanic or Latino314
Not Hispanic or Latino171936
Unknown or Not Reported000
Race (NIH/OMB)
Race (NIH/OMB)(Participants)InterventionAttention-matched ControlTotal
American Indian or Alaska Native000
Asian202
Native Hawaiian or Other Pacific Islander000
Black or African American145
White151328
More than one race235
Unknown or Not Reported000
Region of Enrollment
Region of Enrollment(participants)InterventionAttention-matched ControlTotal
United States202040
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Study locations

1 site
  • Brown University School of Public Health
    Providence, Rhode Island 02901, United States
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References and documents

Study documents

  • Study protocol · Jul 21, 2017
  • Statistical analysis plan · Jul 21, 2017

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Registry details

Key details

Study ID
NCT03435783
Lead sponsor
Brown University
Responsible party
Tyler Wray (Assistant Professor, Brown University) — Principal investigator
First posted
Feb 19, 2018
Start date
Oct 13, 2017
Primary completion
Mar 3, 2018
Completion
Mar 3, 2018
Results posted
Apr 23, 2019
Last update
Apr 23, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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