An interventional study of Buckle and Vitrectomy in Macular Holes, High Myopia and Macular Detachment, sponsored by Sun Yat-sen University. Completed at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-10-09.
Sponsored by Sun Yat-sen University · Not applicable, Interventional, and Treatment
Among 17 studies in Retinal Perforations with a site in China — 4 open to participants now, 6 under way, none of them phase 3. Retinal Perforations · China.
Among the 17 studies in Retinal Perforations with a site in China, this one is the 8th largest by enrollment of the 13 interventional ones, is the only one that started in 2018, is one of 12 with no phase, and was the 7th registered.
139 studies on the registry are indexed under Retinal Perforations; 22 are open to participants now.
This study's enrollment of 50 is close to the median of 50 across 94 interventional studies indexed under Retinal Perforations.
Browse Retinal Perforations studies →4 of the 17 studies in Retinal Perforations with a site in China are open now, in 1 country. Each count lists the studies.
Of the 17 Retinal Perforations studies recruiting now, 15 (88%) set no upper age limit and 1 (6%) stop at 75 or younger; 5 take children under 18; 3 take healthy volunteers.
This study: 18 Years to 70 Years · all sexes · no healthy volunteers.
The full table on the hub →17 studies; the count open now beside each. This study's row is marked.
First in 2005; this study’s year is marked. 1 started in 2018.
Median enrollment 52 across the 13 interventional studies, 240 across the 4 observational. Of the 6 that completed or were terminated, 0 (0%) have results posted.
1 of 17 have an industry lead sponsor. The 10 most frequent:
Sun Yat-sen University is the lead sponsor of 1,690 studies on the registry; 619 are open to participants now.
Sun Yat-sen University has 2 studies filed under Retinal Perforations — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 17 studies in Retinal Perforations with a site in China, from their registry updates:
Nothing recorded among them since 2026-09-25.
Full-thickness macular Hole associated with macular detachment is a one of the maculopathies of high myopia. There is controversy in the primary treatment for this situation. This study will compare the effects of macular buckling versus vitrectomy in a cohort of highly myopic eyes with this situation.
A randomized, open label, single center study comparing the efficacy of macular muckle + gas injection versus internal limiting membrane peeling + gas tamponade on full-thickness macular hole associated with macular detachment in eyes with high myopia.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Macular buckling, Limbal paracentesis, and intraocular gas injection.
Procedure: Buckle · Other: Limbal paracentesis · Other: Gas injection
Vitrectomy, peeling internal limiting membrane, and gas tamponade.
Procedure: Vitrectomy · Other: Peeling internal limiting membrane · Other: Gas tamponade
Surgical procedures of macular buckling
Also known as: Implantation of a device of macular buckling
Surgical procedures of small gauge vitrectomy
Drainage of aqueous fluid (0.1-0.2 ml) through limbal paracentesis
Inject gas ( C3F8 100%, 0.2ml-0.3ml) into vitreous cavity through pars plana.
Peeling internal limiting membrane with forceps
Filling the vitreous cavity with gas (C3F8, 14%)
Retinal re-attachment rate
Successful rate of reattachment of macular retina after surgery
Time frame: 1 month
Macular hole status
Closure rate of macular hole after surgery on optical coherence tomography
Time frame: 3 month
Post-operative best corrected visual acuity
Best corrected visual acuity of the eyes after surgery
Time frame: 3 month
Plan to share: No
Ran from Jan 2018 to primary completion in Jul 2018, 5 months.
Of 45 non-industry interventional studies with no phase under Retinal Perforations, half reached primary completion within 28 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 31. This study's 5 months is below that.
Counting every sponsor, half of 45 studies reached it within 28 months; a quarter within 12 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.
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