An interventional study of Performances of patients and controls on temporal task in Schizophrenia, sponsored by Hôpital le Vinatier. Terminated at 1 site in France. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-01.
Sponsored by Hôpital le Vinatier · Not applicable, Interventional, and Other
People with schizophrenia show disturbances in the perception of time. Among these alterations are the perturbations of the temporal order judgment. They are characterized by the fact that, as opposed to the general population, people with schizophrenia require a longer time interval between two successive stimuli to estimate which of the two events appeared first. If these alterations are now well documented, their consequences remain little explored. Among these consequences could however appear distortions of the judgment of causality (likely to underlie certain delusional interpretations) as well as a distressing experience of loss of the continuity of the lived experience (that could contribute to the alterations basic of self-awareness).
The objective of our work lies in the study of the links between temporal sequencing, subjective perception of time and causality.
To carry out this work, the investigators will rely on an experimental paradigm (derived from Michotte's paradigm) which makes it possible to explore the links between temporal sequencing and perception of causality, validated in the normal subject. subjective consequences of these alterations will be explored using a phenomenological-inspired clinical scale (EAWE time-scale items)
Subjects with schizophrenia:
Control subjects (healthy volunteers):
Exclusion Criteria:
Performances on temporal task Subjective alterations of time perception in patients with an adapted scale (EAWE) Global symptomatology with PANSS (positive and negative symptom scale)
Other: Performances of patients and controls on temporal task
Evaluate the links (correlation) between perception of temporal sequencing and perception of causality using an adapted experimental paradigm (Michotte paradigm) and to compare performance between healthy subjects and controls Investigate the existence of a correlation between these alterations and the peculiarities of the subjective experience of time (EAWE scale) in the group of subjects with schizophrenia
Other: Performances of patients and controls on temporal task
To carry out this work, we will rely on an experimental paradigm (derived from Michotte's paradigm) which makes it possible to explore the links between temporal sequencing and perception of causality, validated in the normal subject. subjective consequences of these alterations will be explored using a phenomenological-inspired clinical scale (EAWE time-scale items)
Comparison of the scores obtained by subjects with schizophrenia vs. the controls for the causal tasks, according to the delays between stimuli (stopping the moving launcher and appearance of the static object).
Michotte paradigm: evaluate the links (correlation) between perception of temporal sequencing and perception of causality using an adapted experimental paradigm
Time frame: eight months
Comparisons of the scores obtained on the Time Experiment Rating Examination of Anomalous World Experience Scale (EAWE).
Examination of Anomalous World Experience (EAWE ) scale:investigate the existence of a correlation between these alterations and the peculiarities of the subjective experience of time The E.A.W.E. consists of 6 dimensions (relation to space / relation to time / relation to others / language / atmospheric experience / existential orientation).The second domain only will be explored in our study Each item is both detailed, on a scale of 0 to 2 (0 for absent, 1 for present but with doubt, 2 for present, no doubt). The overall score of the sub-time scale thus ranges between 0 and 78.
Time frame: eight months
Plan to share: No
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Hôpital le Vinatier