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CompletedNCT03431376Updated Feb 13, 2018

Potato Consumption and Risk of Hypertension

An observational study in Hypertension, sponsored by Zhejiang University. Completed. Open to participants aged 20 Years to 93 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-02-13.

Sponsored by Zhejiang University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
11,763
Ages
20 Years to 93 Years
Sex
All
01

Study summary

Government has popularized potatoes as a major staple food in China. Potato, a potassium-rich food with high glycemic responses after consumption, exhibits unclear effects on hypertension. In this study, the investigators aimed to examine the association between potato consumption and hypertension risk among Chinese people.

Read the detailed description

Potato is considered as a superior crop due to its significant nutritive value and great production yield. China is the largest potato producer with a quarter of world production, followed by India, Russia, and USA. The potato production as well as consumption has enhanced in developing countries while continuously declined in developed countries during the last decade. The investigators therefore explored the prospective associations of consumption of total potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes with the risk of hypertension in general people of the China Health and Nutrition Survey (CHNS) cohort study from 1989 to 2011. A total of 11,763 participants (≥20 years old) who were free of hypertension at baseline were enrolled from CHNS Cohort study. Cox proportional hazards regression models were used to estimate the associations after adjusting for potential confounders. This study provides new evidence on the association of various potato consumption with the incidence of hypertension in China. As urbanization accelerates across the whole domain of China, the tendency of transition to Western-style diets and lifestyles appears continuously and steeply growing. More and more potatoes will be consumed as processed potato products including potatoes chips and French fries, which may be a potential risk factor of hypertension occurrence.

02

Conditions studied

  • Hypertension

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Keywords

  • potato consumption
  • hypertension
  • CHNS
03

Who can participate

Ages eligible
20 Years to 93 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Of the 11,763 participants, 5,344 male and 6,419 female were enrolled, ranging from 20 to 93 years old. People who consumed the potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes accounted for 57.3%, 15.0%, 51.8%, and 28.1%, respectively. There were about 90.4% people who consumed the potatoes through the stir-frying method.

Inclusion criteria

  • Adults aged 20-93 with complete data on diet and follow-up time
  • Adults with no chronic disease history

Exclusion criteria

Exclusion Criteria:

  • Adults aged \< 20 years
  • Identified to be pregnant
  • Previously diagnosed with hypertension, cancers, infarction, apoplexy, and diabetes
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
11,763 participants (actual)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Hypertension

    Incidence of hypertension, on basis of self-reported physician diagnosis, systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or previous diagnose of hypertension by a physician or current use of anti-hypertensive drugs

    Time frame: From entry into the study (baseline: 1989-2009) until 2011

Secondary outcomes

  1. Potato consumption

    The frequency and the quantity of daily average consumption of total potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes (g/day) based on 3-day 24-hr recall

    Time frame: From entry into the study (baseline: 1989-2009) until 2011

06

Study locations

No study locations are listed for this record.

07

Registry details

Key details

Study ID
NCT03431376
Lead sponsor
Zhejiang University
Responsible party
Yu Zhang (Professor, Zhejiang University) — Principal investigator
First posted
Feb 13, 2018
Start date
Jan 1, 1989
Primary completion
Dec 31, 2011
Completion
Feb 1, 2018
Last update
Feb 13, 2018

Study contacts

Jingjing Jiao, PhD
study director · Zhejiang University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.

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