An observational study in Asthma, COPD and Asthma-COPD Overlap Syndrome, sponsored by Mahidol University. Completed at 1 site in Thailand. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-06-18.
Sponsored by Mahidol University · Observational
This study was designed as retrospective chart review to test our hypothesis whether there are the differences in inflammatory and anti-inflammatory mediators between asthmatic and ACOS patients with small airway obstruction, and COPD
The data including spirometry, lung volume, impulse oscillometry, sputum data, demographic characters within 6 months are collected for later analysis. Sputum supernatants and cytospins are used to determine inflammatory and anti-inflammatory responses in those patients.
4,012 studies on the registry are indexed under Asthma; 514 are open to participants now.
This study's enrollment of 230 is above the median of 150 across 993 observational studies indexed under Asthma.
Browse Asthma studies →Mahidol University is the lead sponsor of 744 studies on the registry; 116 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Participants recruited from Asthma Clinics and OPD in Siriraj Hospital
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Asthmatic patients with RV/TLC \> or = 40
Other: No any intervention
Asthmatic patients with RV/TLC \< 40
Other: No any intervention
Asthmatic patients with smoking \> or = 10 pack years who have persistent airway obstruction (post-BD FEV1/FVC \< 0.7) or COPD patients who have bronchodilator (BD) reversibility (absolute increase in FEV1 \> or = 200 ml and FEV1% \> or =12% after BD)
Other: No any intervention
Patients with history of smoking \> or = 10 pack year with post-BD FEV1/FVC \< 0.7 and negative BD reversibility (absolute increase in FEV1 \< 200 ml and FEV1% \<12% after BD)
Other: No any intervention
No any intervention is applied to any groups in this study
Lipoxin A4, ,
Lipoxin A4 is measured in sputum supernatants by ELISA
Time frame: 1 day (single time point)
IL-33
IL-33 is measured in sputum supernatants by ELISA
Time frame: 1 day (single time point)
Thymic stromal lymphopoietin (TSLP)
TSLP is measured in sputum supernatants by ELISA
Time frame: 1 day (single time point)
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2018 to primary completion in Jul 2020, 30 months.
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This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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