An interventional study of CTR and MICT in Obesity and Metabolic Syndrome, sponsored by University of Sao Paulo. Completed. Open to female participants aged 25 Years to 41 Years. Per ClinicalTrials.gov, last updated 2018-01-24.
Sponsored by University of Sao Paulo · Not applicable, Interventional, and Treatment
The main purpose of this study is to compare the effects of high intensity interval training and moderate intensity continuous training on inflammatory profile and metabolic markers, after 8 weeks of intervention trial in obese women.
11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.
This study's enrollment of 48 is below the median of 67 across 9,006 interventional studies indexed under Obesity.
Browse Obesity studies →University of Sao Paulo is the lead sponsor of 1,035 studies on the registry; 95 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
No counseling or nutritional therapy and no exercise
Other: CTR
Follow-up during a period of 8 weeks of supervised ergometer-based moderate-intensity continuous training based on HRmax (MICT). MICT: * 3 sessions per week * intensity at 65-75% HRmax * time-effort per session: 50 min
Other: MICT
Procedures: Follow-up during a period of 8 weeks of supervised ergometer-based high intensity interval training based on HRmax (HIIT). HIIT: * 3 sessions per week * 10 bouts of one minute at 90% HRmax interspersed by one minute at 40% HRmax * time-effort per session: 25 min
Other: HIIT
no counseling or nutritional therapy and no exercise
no counseling or nutritional therapy. 8 weeks of individualized and supervised ergometer-based moderate continuous intensity training (MICT).
no counseling or nutritional therapy. 8 weeks of individualized and supervised ergometer-based high intensity interval training (HIIT)
Inflammatory profile
C-reactive protein (CRP) (mg/dL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Inflammatory profile
Interleukin 6 (IL-6) (ng/mL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Inflammatory profile
Interleukin 10 (IL-10) pg/mL, Interleukin-1B (IL-1B) pg/mL, Tumor Necrosis Factor (TNF)-α (pg/mL), Adiponectin (pg/mL), Monocyte chemoattractant protein 1 (MCP-1) (pg/mL), Leptin (pg/mL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Body Composition and Anthropometric profile
Body weight (kg), Fat free mass (FFM) (kg), fat mass (FM) (kg)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Body Mass Index (BMI) (kg/m²)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Waist circumference (cm), hip circumference (cm)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Body Adiposity Index (BAI) and Waist-To-Hip Ratio (WHR)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Insulin sensitivity
Insulin sensitivity was estimated using homeostasis model assessment index (HOMA)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Lipid profile
Lipid profile was assessed by measuring levels of triglyceride (TG) (mg/dL), total cholesterol (CT) (mg/dL), high-density lipoprotein cholesterol (HDL-C) (mg/dL) and low-density lipoprotein cholesterol (LDL-C) (mg/dL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Cardiorespiratory Fitness (CRF)
CRF was assessed by measuring Peak Oxygen uptake (VO2peak) mL/kg/min
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Blood Pressure (BP)
Blood Pressure (mmHg) was assessed by measuring rest levels of Systolic blood pressure (SBP) and Diastolic blood pressure (DBP)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Resting Energy Expenditure (REE)
Resting Energy Expenditure (kcal/day) was measured through indirect calorimetry with an open-circuit ventilated-hood system Substrate oxidation rate was calculated from VO2 (mL/min) and VCO2 (mL/min)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Substrate oxidation rate
Substrate oxidation rate was calculated from VO2 (mL/min) and VCO2 (mL/min)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Ran from Jun 2016 to primary completion in Jan 2018, 19 months.
Of 3,680 non-industry interventional studies with no phase under Obesity, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 43. This study's 19 months is below that.
Counting every sponsor, half of 3,843 studies reached it within 22 months; a quarter within 10 and three quarters within 42.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.