An observational study in Pleura; Effusion, sponsored by Charite University, Berlin, Germany. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-06-09.
Sponsored by Charite University, Berlin, Germany · Observational
Pleural effusions occur commonly in patients recovering from cardiac surgery, however, the impact on outcomes is not well characterized. The purpose of this study is to characterize the outcomes of cardiac surgery patients with pleural effusions.
All patients undergoing cardiac surgery between 2006 and 2019 were included in this observational, cross-sectional analysis using propensity matching.
Pleural effusions are common in patients recovering from cardiac surgery. Symptomatic patients with pleural effusions complain of shortness of breath, cough, chest pain and are more hypoxic and tachypneic. Clinically significant effusions can slow recovery in the hospital and beyond, and are a critical source of hospital readmissions after discharge. It is not well characterized how this impacts hospital outcomes. Further it is unknown if the effusions themselves are associated with impaired outcomes, or if pleural effusions simply arise in more complicated, older patients, thus suggesting the impaired outcomes are the result of coexisting morbidities. To better understand the impact of this complication and to address the question mentioned before, this study was carried out to determine the clinical and economic outcomes of pleural effusions in propensity-matched patients during early recovery from cardiac surgery. To compare patient groups with and without pleural effusion, the following baseline characteristics were used: e.g. age, sex, body-mass-index, priority of surgery, type of surgery, duration of surgery, APACHE II Score of patients on admission in the ICU.
All adult male and female patients who have undergone cardiac surgery in the period 01/06-12/19 at Campus Mitte in the Charité, approx. 11,000 patients.
Exclusion Criteria:
patients without pleural effusion
patients with pleural effusion
patients with pleural Effusion and need of drainage
mortality
In-Hospital mortality
Time frame: an average of 30 days
hospital stay
Length of hospital stay
Time frame: an average of 30 days
Need of drainage
Incidence of drainage in patients with pleural effusions
Time frame: an average of 30 days
extubation
time to extubation
Time frame: an average of 15 hours
renal replacement
incidence of renal replacement therapy
Time frame: an average of 30 days
transfusions
number of transfusions needed
Time frame: an average of 30 days
ICU stay
Length of Intensive Care Unit (ICU) stay
Time frame: an average of 15 days
This study is completed, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.
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Charite University, Berlin, Germany